879275-33-9

Usage

Uses

Used in Pharmaceutical Industry:
N-[(3R)-3-piperidinylmethyl]-carbamic acid 1,1-dimethylethyl ester is used as an intermediate in the synthesis of pharmaceuticals and organic compounds. Its role in this industry is crucial for the development of new drugs, as it can contribute to enhancing the properties of existing medications or facilitating the creation of novel therapeutic agents.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, N-[(3R)-3-piperidinylmethyl]-carbamic acid 1,1-dimethylethyl ester serves as a valuable component in research. It is employed for studying the structure-activity relationships of drug molecules and for probing the mechanisms of drug action, thereby aiding in the design of more effective and safer pharmaceuticals.
Used in Organic Synthesis:
N-[(3R)-3-piperidinylmethyl]-carbamic acid 1,1-dimethylethyl ester is also used as a reagent or building block in organic synthesis. Its presence in this field is significant for the construction of complex organic molecules, which can have applications in various industries, including materials science, agrochemicals, and specialty chemicals.

InChI:InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-8-9-5-4-6-12-7-9/h9,12H,4-8H2,1-3H3,(H,13,14)

Upstream product

• 142643-29-6 tert-butyl (piperidin-3-ylmethyl)carbamate 

Downstream Products

• 1391739-80-2 tert-butyl ((S)-1-((S)-1-(4-methylbenzyl)-5-oxopyrrolidine-2-carbonyl)piperidin-3-yl)methylcarbamate 
• 1615250-04-8 tert-butyl ((S)-1-((R)-3-(4-methylbenzyl)thiazolidine-4-carbonyl)piperidin-3-yl)methylcarbamate 
• 1615249-95-0 tert-butyl ((S)-1-((S)-1-(4-cyanobenzyl)-5-oxopyrrolidine-2-carbonyl)piperidin-3-yl)methylcarbamate 
• 1615249-91-6 tert-butyl ((S)-1-((S)-1-(2,6-dichlorobenzyl)-5-oxopyrrolidine-2-carbonyl)piperidin-3-yl)methylcarbamate 
• 1615249-87-0 tert-butyl ((S)-1-((S)-1-(4-bromobenzyl)-5-oxopyrrolidine-2-carbonyl)piperidin-3-yl)methylcarbamate 
• 1615249-83-6 tert-butyl ((S)-1-((S)-1-(4-chlorobenzyl)-5-oxopyrrolidine-2-carbonyl) piperidin-3-yl)methylcarbamate 
• 1615250-03-7 tert-butyl ((S)-1-((R)-3-(4-methylbenzyl)-2-oxothiazolidine-4-carbonyl)piperidin-3-yl)methylcarbamate 
• 1615250-02-6 tert-butyl ((S)-1-((S)-3-(4-methylbenzyl)-2-oxooxazolidine-4-carbonyl)piperidin-3-yl)methylcarbamate 
• 1615249-93-8 tert-butyl ((S)-1-((S)-1-(3-cyanobenzyl)-5-oxopyrrolidine-2-carbonyl)piperidin-3-yl)methylcarbamate 
• 1615249-89-2 tert-butyl ((S)-1-((S)-1-(3,4-dichlorobenzyl)-5-oxopyrrolidine-2-carbonyl)piperidin-3-yl)methylcarbamate 
• 1016167-77-3 C₂₇H₃₇N₇O₄ 
• 879275-42-0 2-(4-((S)-3-(aminomethyl)piperidin-1-yl)-7-methylquinazolin-2-yl)-3-fluorophenol 
• 1615249-85-8 tert-butyl ((S)-1-((S)-1-(2-bromobenzyl)-5-oxopyrrolidine-2-carbonyl) piperidin-3-yl)methylcarbamate 
• 1615250-11-7 tert-butyl ((S)-1-((S)-4-(4-methylbenzyl)-5-oxothiomorpholine-3-carbonyl)piperidin-3-yl)methylcarbamate 

Relevant academic research and scientific papers

CHIRAL 1-(4-METHYLPHENYLMETHYL)-5-OXO-{N-[(3-T-BUTOXYCARBONYL- AMINOMETHYL)]-PIPERIDIN-1-YL}-PYRROLIDINE-2-CARBOXAMIDES AS INHIBITORS OF COLLAGEN INDUCED PLATELET ACTIVATION AND ADHESION

Chiral l-(4-methylphenylmethyl)-5-oxo-{N-[(3-t-butoxycarbonyl-aminomethyl)]- piperidin-l-yl}-pyrrolidine-2-carboxamides as inhibitors of collagen induced platelet activation and adhesion The present invention provides chiral (2S)-l-(4-methylphenylmethyl)-5-oxo-(3S)-{N-[(3-t- butoxycarbonyl aminomethyl)]-piperidin-l-yl}-pyrrolidine-2-carboxamide, and (2S)-1-(4- methylphenylmethyl)-5-oxo-(3R)-{N-[(3-t-butoxycarbonyl amino methyl)]-piperidin-l-yl}- pyrrolidine-2-carboxamide of formula 6 and 7 respectively. The present invention also relates to use of these moieties as inhibitors of collagen induced platelet adhesion and aggregation mediated through collagen receptors. The present invention provides a process for preparation of chiral carboxamides of formula 6 and 7 using the process which has advantage to avoid any racemization at the a-carboxylic center, during N-alkylation. The reagent LiHMDS is used at low temperatures to furnish methyl N-(p- methylphenylmethyl)lpyroglutamate in good chiral purity.

QUINAZOLINES USEFUL AS MODULATORS OF ION CHANNELS

The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.