879398-89-7 Usage
Molecular structure
1H-Pyrrolo[2,3-c]pyridine-5-carboxylic acid, 1-[(4-fluorophenyl)methyl]-3-[(3-hydroxy-1-pyrrolidinyl)methyl]-, methyl ester is an organic compound with a complex molecular structure that includes a pyrrolopyridine core, a carboxylic acid group, a fluorophenylmethyl group, a hydroxy-pyrrolidinylmethyl group, and a methyl ester functional group.
Core structure
The compound has a pyrrolopyridine core, which is a fusion of a pyrrole and a pyridine ring, providing a stable and rigid structure.
Carboxylic acid group
The presence of a carboxylic acid group (-COOH) in the molecule contributes to its acidity and may be involved in hydrogen bonding and other interactions with biological targets.
Fluorophenylmethyl group
The 4-fluorophenylmethyl group (-CH2C6H4F) is an electron-withdrawing group that may influence the electronic properties of the molecule and contribute to its biological activity.
Hydroxy-pyrrolidinylmethyl group
The 3-hydroxy-1-pyrrolidinylmethyl group (-CH2CH2CH2OH) introduces a hydroxyl group into the molecule, which can participate in hydrogen bonding and may affect the compound's solubility and bioavailability.
Methyl ester functional group
The methyl ester group (-COOCH3) is present in the molecule, which can influence its lipophilicity and may affect its ability to cross cell membranes and reach target sites in the body.
Pharmaceutical applications
Due to its structural features, 1H-Pyrrolo[2,3-c]pyridine-5-carboxylic acid,
1-[(4-fluorophenyl)methyl]-3-[(3-hydroxy-1-pyrrolidinyl)methyl]-, methyl
ester may have potential pharmaceutical applications, such as acting as a modulator of specific biological targets or exhibiting therapeutic effects in the human body.
Further research
Additional studies are needed to investigate the properties, potential uses, and safety profile of 1H-Pyrrolo[2,3-c]pyridine-5-carboxylic acid,
1-[(4-fluorophenyl)methyl]-3-[(3-hydroxy-1-pyrrolidinyl)methyl]-, methyl
ester to determine its suitability for various applications in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 879398-89-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,9,3,9 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 879398-89:
(8*8)+(7*7)+(6*9)+(5*3)+(4*9)+(3*8)+(2*8)+(1*9)=267
267 % 10 = 7
So 879398-89-7 is a valid CAS Registry Number.
879398-89-7Relevant academic research and scientific papers
Azaindole N-methyl hydroxamic acids as HIV-1 integrase inhibitors-II. the impact of physicochemical properties on ADME and PK
Tanis, Steven P.,Plewe, Michael B.,Johnson, Ted W.,Butler, Scott L.,Dalvie, Deepak,Delisle, Dorothy,Dress, Klaus R.,Hu, Qiyue,Huang, Buwen,Kuehler, Jon E.,Kuki, Atsuo,Liu, Wen,Peng, Qinghai,Smith, Graham L.,Solowiej, Jim,Tran, Khanh T.,Wang, Hai,Yang, Anle,Yin, Chunfeng,Yu, Xiaoming,Zhang, Junhu,Zhu, Huichun
supporting information; experimental part, p. 7429 - 7434 (2011/02/26)
HIV-1 integrase is one of three enzymes encoded by the HIV genome and is essential for viral replication, and HIV-1 IN inhibitors have emerged as a new promising class of therapeutics. Recently, we reported the discovery of azaindole hydroxamic acids that
INHIBITORS OF THE HIV INTEGRASE ENZYME
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Page/Page column 66, (2010/10/20)
The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, pharmaceutical compositions comprisingm compounds of formula (I), and their methods of use in treating HIV-infected mammals.
