87942-08-3

Basic information

• Product Name: 4-N-PROPYLPHENYLMAGNESIUM BROMIDE
• Synonyms: 4-N-PROPYLPHENYLMAGNESIUM BROMIDE;4-N-PROPYLPHENYLMAGNESIUM BROMIDE, 0.5M&;4-n-propylphenylmagnesium bromide solution;4-n-Propylphenylmagnesium bromide solution 0.5 in THF;4-n-Propylphenylmagnesium bromide, 0.5M solution in THF, AcroSeal;4-n-PropylphenylMagnesiuM broMide, 0.5M solution in THF, J&KSeal;4-n-Propylphenylmagnesium bromide solution 0.5M in THF
• CAS NO: 87942-08-3
• Molecular Formula: C₉H₁₁BrMg
• Molecular Weight: 223.39
• Product Categories: Aryl;Grignard Reagents;Organometallic Reagents;Chemical Synthesis;Grignard Reagents;Organometallic Reagents;Grignard Reagent
• Mol File: 87942-08-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 65-67 °C(lit.)
• Flash Point: 1 °F
• Appearance: Brown/Liquid
• Density: 0.940 g/mL at 25 °C(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-N-PROPYLPHENYLMAGNESIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-N-PROPYLPHENYLMAGNESIUM BROMIDE(87942-08-3)
• EPA Substance Registry System: 4-N-PROPYLPHENYLMAGNESIUM BROMIDE(87942-08-3)

Safety Data

• Hazard Codes: F,C
• Statements: 11-14-19-34-40-37
• Safety Statements: 16-29-33-45-36/37/39-26
• RIDADR: UN 2924 3/PG 2
• WGK Germany: 1
• Hazardous Substances Data: 87942-08-3(Hazardous Substances Data)

Usage

General Description

4-N-PROPYLPHENYLMAGNESIjson BROMIDE is an organometallic compound with the chemical formula C9H13BrMg. It is commonly used as a reagent in organic synthesis, particularly for the Grignard reaction, where it acts as a source of the propyl phenylmagnesium nucleophile. 4-N-PROPYLPHENYLMAGNESIUM BROMIDE is an important tool in the production of various organic molecules, especially in the pharmaceutical and fine chemical industries. It is a highly reactive compound and should be handled with caution due to its flammability and potential for spontaneous ignition in air.

InChI:InChI=1/C9H11.BrH.Mg/c1-2-6-9-7-4-3-5-8-9;;/h4-5,7-8H,2,6H2,1H3;1H;/q;;+1/p-1/rC9H11BrMg/c1-2-3-8-4-6-9(11-10)7-5-8/h4-7H,2-3H2,1H3

Upstream product

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Downstream Products

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Relevant articles and documents

Methods of using α-phosphonosulfonate squalene synthetase inhibitors including the treatment of atherosclerosis and hypercholesterolemia

α-Phosphonosulfonate compounds are provided which inhibit the enzyme squalene synthetase and thereby inhibit cholesterol biosynthesis. These compounds have the formula STR1 wherein R2 is OR5 or R5a ; R3 and R5 are independently H, alkyl, arylalkyl, aryl or cycloalkyl; R5a is H, alkyl, arylalkyl or aryl; R4 is H, alkyl, aryl, arylalkyl, or cycloalkyl;, Z is H, halogen, lower alkyl or lower alkenyl; and R1 is a lipophilic group which contains at least 7 carbons and is alkyl, alkenyl, alkynyl, mixed alkenyl-alkynyl, aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, heteroaryl, heteroarylalkyl, cycloheteroalkyl, cycloheteroalkylalkyl; as further defined above; including pharmaceutically acceptable salts and or prodrug esters of the phosphonic (phosphinic) and/or sulfonic acids.