87942-08-3 Usage
Uses
Used in Organic Synthesis:
4-N-PROPYLPHENYLMAGNESIUM BROMIDE is used as a reagent for the Grignard reaction, a fundamental method in organic chemistry for the formation of carbon-carbon bonds. It is employed for this purpose due to its ability to act as a nucleophile, facilitating the reaction and leading to the formation of desired organic compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 4-N-PROPYLPHENYLMAGNESIUM BROMIDE is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its role in the Grignard reaction allows for the creation of complex organic molecules that are integral to the development of new drugs and medicinal agents.
Used in Fine Chemical Industry:
Similarly, in the fine chemical industry, 4-N-PROPYLPHENYLMAGNESIUM BROMIDE is used as a reagent for the synthesis of specialty chemicals. These fine chemicals often have specific applications in areas such as fragrances, dyes, and other high-value chemical products, where the precision and selectivity of the Grignard reaction are particularly advantageous.
Safety Considerations:
Given the compound's high reactivity and flammability, 4-N-PROPYLPHENYLMAGNESIUM BROMIDE is used with strict safety protocols in place. This includes handling under an inert atmosphere to prevent spontaneous ignition and taking necessary precautions to avoid contact with air or other reactive substances.
Check Digit Verification of cas no
The CAS Registry Mumber 87942-08-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,9,4 and 2 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 87942-08:
(7*8)+(6*7)+(5*9)+(4*4)+(3*2)+(2*0)+(1*8)=173
173 % 10 = 3
So 87942-08-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H11.BrH.Mg/c1-2-6-9-7-4-3-5-8-9;;/h4-5,7-8H,2,6H2,1H3;1H;/q;;+1/p-1/rC9H11BrMg/c1-2-3-8-4-6-9(11-10)7-5-8/h4-7H,2-3H2,1H3
87942-08-3Relevant academic research and scientific papers
Methods of using α-phosphonosulfonate squalene synthetase inhibitors including the treatment of atherosclerosis and hypercholesterolemia
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, (2008/06/13)
α-Phosphonosulfonate compounds are provided which inhibit the enzyme squalene synthetase and thereby inhibit cholesterol biosynthesis. These compounds have the formula STR1 wherein R2 is OR5 or R5a ; R3 and R5 are independently H, alkyl, arylalkyl, aryl or cycloalkyl; R5a is H, alkyl, arylalkyl or aryl; R4 is H, alkyl, aryl, arylalkyl, or cycloalkyl;, Z is H, halogen, lower alkyl or lower alkenyl; and R1 is a lipophilic group which contains at least 7 carbons and is alkyl, alkenyl, alkynyl, mixed alkenyl-alkynyl, aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, heteroaryl, heteroarylalkyl, cycloheteroalkyl, cycloheteroalkylalkyl; as further defined above; including pharmaceutically acceptable salts and or prodrug esters of the phosphonic (phosphinic) and/or sulfonic acids.
Synthesis and Liquid Crystal Behaviour of Further 4,4"-Disubstituted 2'-Fluoro-1,1':4',1"-Terphenyls
Chan, L. K. M.,Gray, G. W.,Lacey, D.,Toyne, K. J.
, p. 209 - 240 (2007/10/02)
Further to earlier work on the liquid crystal properties of fluoro-1,1':4',1"-terphenyls we have now extended this series to include terminally fluoro- and cyano-substituted 2'-fluoro-1,1':4',1"-terphenyls, chiral 2'-fluoro-1,1':4',1"-terphenyls, and esters derived from 2'-fluoro-1,1':4',1"-terphenyls and incorporating the alkylcyclobutyl group.The preparations and transition temperatures for these series of compounds are presented and their transition temperatures and mesophase types are discussed.An interesting result from this work was the appearence of an S*C phase for one chiral homologue and of SC phases for the esters incorporating the alkylcyclobutyl group.The SC formation is attributed to the presence of the fluoro-substituent.Keywords: terphenyls, fluoroterphenyls, smectic C phases, cyclobutyl esters.
