87943-95-1

Upstream product

• 22027-51-6 3-oxo-3-p-tolyl-propionic acid methyl ester 

Downstream Products

• 1421922-26-0 2-(4-amino-2,5-dimethylbenzyl)-4-(4-methylphenyl)-1,3-thiazole-5-carboxamide 
• 1421922-25-9 2-(2,5-dimethyl-4-nitrobenzyl)-4-(4-methylphenyl)-1,3-thiazole-5-carboxamide 
• 1421922-24-8 2-(4-amino-2,5-dimethylbenzyl)-N-methyl-4-(4-methylphenyl)-1,3-thiazole-5-carboxamide 
• 1421922-23-7 2-(2,5-dimethyl-4-nitrobenzyl)-N-methyl-4-(4-methylphenyl)-1,3-thiazole-5-carboxamide 
• 1421922-22-6 2-(2,5-dimethyl-4-nitrobenzyl)-4-(4-methylphenyl)-1,3-thiazole-5-carboxylic acid 
• 1421922-21-5 methyl 2-(4-amino-2,5-dimethylbenzyl)-4-(4-methylphenyl)-1,3-thiazole-5-carboxylate 
• 1421921-07-4 2-[4-({(E)-[ethyl(methyl)amino]methylidene}amino)-2,5-dimethylbenzyl]-N-methyl-4-(4-methylphenyl)-1,3-thiazole-5-carboxamide 
• 1421921-06-3 2-[4-({(E)-[ethyl(methyl)amino]methylidene}amino)-2,5-dimethylbenzyl]-4-(4-methylphenyl)-1,3-thiazole-5-carboxamide 
• 1421921-02-9 2-[4-({(E)-[ethyl(methyl)amino]methylidene}amino)-2,5-dimethylbenzyl]-4-(4-methylphenyl)-1,3-thiazole-5-carboxylic acid 
• 1421922-20-4 methyl 2-(2,5-dimethyl-4-nitrobenzyl)-4-(4-methylphenyl)-1,3-thiazole-5-carboxylate 
• 87944-08-9 methyl 2-dimethylamino-4-(methylphenyl)thiazole-5-carboxylate 

Relevant academic research and scientific papers

AMIDINE COMPOUND OR SALT THEREOF

The purpose of the present invention is to provide a novel compound which has an anti-fungal activity on pathogenic fungi including fungi belonging to the genus Candida, the genus Aspergillus and the genus Trichophyton and is useful as a medicinal agent. A compound represented by formula (I) (wherein A1 represents a nitrogen atom or a group represented by formula CR6; A2 and A3 are the same as or different from each other and independently represent a nitrogen atom or a group represented by formula CH; R1 represents an aryl group which may be substituted by 1 to 5 substituents independently selected from a substituent group (2) or the like; R2 and R3 are the same as or different from each other and independently represent a hydrogen atom, a halogen atom, a C1-6 alkyl group, a C1-6 haloalkyl group or a C1-6 alkoxy group; and R4 and R5 are the same as or different from each other and independently represent a hydrogen atom, a C1-6 haloalkyl group, a C1-6 alkyl group or the like) or a salt thereof is useful as an anti-fungal agent.