87953-86-4Relevant academic research and scientific papers
With 5, 2 '- dihydroxy - 4' - methoxy - 3 - geranyl flavone skeleton derivative and its preparation and use
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Paragraph 0042-0043; 0062; 0082, (2017/10/26)
The invention discloses a derivative with a 5,2'-dihydroxy-4'-methoxy-3-geranylated flavone framework and a preparation method for the derivative and use of the derivative. The derivative is represented by the chemical general formula (I) or is pharmaceutically acceptable salts thereof: the formula (I) is shown in the description, wherein R1 represents -OCH3 or -OH, R2 is -Cl or -Br, R3 is -OCH3 or -OH, and R4 is -OCH3 or -OH. The obtained derivative has good cervical cancer resisting activity, has multiple target points, multiple links and multiple effects, is low in toxicity and is not easy to cause drug resistance.
SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS
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Page/Page column 16-17, (2008/12/06)
The invention provides compounds of Formula (1) or a pharmaceutically acceptable salt of said compound, wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating mammals suffering from the condition of being overweight.
Aromatic derivatives comprising an aminoalkoxy chain and pharmaceutical compositions thereof
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, (2008/06/13)
New aromatic derivatives having an activity antagonistic to calcium and corresponding to formula: STR1 in which: A represents a chain having any one of the following structures: STR2 Ar represents a group of structure: STR3 n takes the value 1 or 2 when R
5,8-Quinoflavone. Synthesis and Addition Reactions
Looker, James H.,Edman, James R.,Kingsbury, Charles A.
, p. 645 - 649 (2007/10/02)
A synthesis of 5,8-quinoflavone (3) from primetin (2) is described.An improved Elbs persulfate oxidation procedure for 2 is presented.Addition of halogens and of hydrogen chloride to 3 is described, together with chemical and spectral data establishing th
