879564-86-0
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Basic information
- Product Name: ANTI-AMYLOID, BETA
- Synonyms: PAN BETA-AMYLOID (AB-1) POLYCLONAL ANTIBODY;MONOCLONAL ANTI-BETA-AMYLOID;ANTI-BETA-AMYLOID PROTEIN;ANTI-BETA-AMYLOID RABBIT PAB;ANTI-BETA AMYLOID;ANTI-AMYLOID BETA-PEPTIDE;ANTI-AMYLOID, BETA;ANTI-ABETA
- CAS NO:879564-86-0
- Molecular Formula: C11H10ClNO2
- Molecular Weight: 223.6556
- EINECS: N/A
- Product Categories: N/A
- Mol File: 879564-86-0.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: white to off-white/buffered aqueous solution
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: DMSO: ≥50mg/mL
- CAS DataBase Reference: ANTI-AMYLOID, BETA(CAS DataBase Reference)
- NIST Chemistry Reference: ANTI-AMYLOID, BETA(879564-86-0)
- EPA Substance Registry System: ANTI-AMYLOID, BETA(879564-86-0)
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Safety Data
- Hazard Codes: Xn
- Statements: 22
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 879564-86-0(Hazardous Substances Data)
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879564-86-0 Usage
Uses
The antibody is useful in immunohistochemistry, immunoblotting, ELISA, and competitive ELISA. Also, this antibody has been used to neutralize Aβ assemblies in brains of transgenic mice expressing a mutant form of amyloid precursor protein, and for in vivo deep tissue imaging using near-IR optical spectrum.General Description
The antibody reacts specifically with β-amyloid protein. The epitope recognized by the antibody resides within amino acids 1-12 of the β-amyloid protein. It specifically stains amyloid plaques within the cortex and amyloid deposits in blood vessels using formic acid-treated, formalin-fixed, paraffin-embedded, and Methacarn-fixed sections of human Alzheimer′s disease (AD) brain tissue.Biochem/physiol Actions
β-amyloid gene acts as the substrate of insulin-degrading enzyme (IDE). It plays a major role in the pathogenesis of Alzheimer′s disease (AD) and type 2 diabetes mellitus (DM2).Check Digit Verification of cas no
The CAS Registry Mumber 879564-86-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,9,5,6 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.Calculate Digit Verification of CAS Registry Number 879564-86:
(8*8)+(7*7)+(6*9)+(5*5)+(4*6)+(3*4)+(2*8)+(1*6)=250
250 % 10 = 0
So 879564-86-0 is a valid CAS Registry Number.
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ANTI-AMYLOID, BETA
