87959-45-3

Basic information

• Product Name: 1-(2,2-dibromo-1-methylcyclopropyl)-4-methylbenzene
• Synonyms: 1-(2,2-dibromo-1-methylcyclopropyl)-4-methylbenzene
• CAS NO: 87959-45-3
• Molecular Weight: 304.024
• Mol File: 87959-45-3.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 1-(2,2-dibromo-1-methylcyclopropyl)-4-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,2-dibromo-1-methylcyclopropyl)-4-methylbenzene(87959-45-3)
• EPA Substance Registry System: 1-(2,2-dibromo-1-methylcyclopropyl)-4-methylbenzene(87959-45-3)

Safety Data

• Hazardous Substances Data: 87959-45-3(Hazardous Substances Data)

Upstream product

• 122-00-9 para-methylacetophenone 
• 1195-32-0 1-methyl-4-isopropenylbenzene 
• 75-25-2 Bromoform 

Downstream Products

• 63099-51-4 1-(buta-2,3-dien-2-yl)-4-methylbenzene 
• 87959-70-4 1-Methyl-4-((E)-1-methyl-but-1-en-3-ynyl)-benzene 
• 87959-55-5 1-(2,2-Dibromo-1-methyl-3-methylene-cyclopropyl)-4-methyl-benzene 
• 87959-62-4 1-(2-Dibromomethylene-1-methyl-cyclopropyl)-4-methyl-benzene 
• 1592-34-3 2,3-diethoxybutane 
• 1064001-35-9 1-methyl-4-(1-methyl-2-cyclopropen-1-yl)benzene 

Relevant articles and documents

Enantioselective Hydrothiolation: Diverging Cyclopropenes through Ligand Control

In this article, we advance Rh-catalyzed hydrothiolation through the divergent reactivity of cyclopropenes. Cyclopropenes undergo hydrothiolation to provide cyclopropyl sulfides or allylic sulfides. The choice of bisphosphine ligand dictates whether the pathway involves ring-retention or ring-opening. Mechanistic studies reveal the origin for this switchable selectivity. Our results suggest the two pathways share a common cyclopropyl-Rh(III) intermediate. Electron-rich Josiphos ligands promote direct reductive elimination from this intermediate to afford cyclopropyl sulfides in high enantio- A nd diastereoselectivities. Alternatively, atropisomeric ligands (such as DTBM-BINAP) enable ring-opening from the cyclopropyl-Rh(III) intermediate to generate allylic sulfides with high enantio- A nd regiocontrol.

A convenient access to allylic triflones with allenes and triflyl chloride in the presence of (EtO)2P(O)H

A simple method for the preparation of allylic triflones from allenes and triflyl chloride in the presence of (EtO)2P(O)H has been developed. The features of this reaction are catalyst-free and simple starting substrates. This method tolerates diverse functional groups and substituted allylic triflones are obtained in moderate to good yields.

Regioselective Diboron-Mediated Semireduction of Terminal Allenes

A method for the regioselective reduction of the terminal double bond of 1,1-disubstituted allenes has been developed. In the presence of a palladium catalyst, tetrahydroxydiboron and stoichiometric water, allene semireduction proceeds in high yield to afford Z-alkenes selectively.