879614-93-4 Usage
Uses
Used in Pharmaceutical Industry:
(5-AMINO-2-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER is used as a building block for the synthesis of various drugs and pharmaceutical compounds. Its role in the development of new therapeutic agents is significant, given its ability to selectively inhibit HDAC6, which is a target for treatments in certain cancers and neurodegenerative diseases.
Used in Cancer Treatment Research:
In the field of oncology, (5-AMINO-2-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER is used as a potential therapeutic agent for the treatment of cancer. Its mechanism of action involves the selective inhibition of HDAC6, which can lead to the modulation of gene expression and cellular functions, thereby affecting the growth and survival of cancer cells.
Used in Neurodegenerative Disease Research:
(5-AMINO-2-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER is also being studied for its potential therapeutic effects in neurodegenerative diseases. Given the involvement of HDAC6 in protein aggregation and cellular stress responses, (5-AMINO-2-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER may offer a means to address some of the underlying pathological processes in such conditions.
Used as a Reagent in Organic Synthesis:
Beyond its direct applications in medicine, (5-AMINO-2-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER serves as a reagent in organic synthesis. It is utilized in the preparation of other useful compounds, contributing to the broader scope of chemical research and development.
Used as a Precursor in Chemical Production:
In the chemical industry, (5-AMINO-2-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER is used as a precursor for the preparation of other compounds. Its versatility in chemical reactions makes it a valuable intermediate in the synthesis of a range of products, extending its utility beyond the pharmaceutical sector.
Check Digit Verification of cas no
The CAS Registry Mumber 879614-93-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,9,6,1 and 4 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 879614-93:
(8*8)+(7*7)+(6*9)+(5*6)+(4*1)+(3*4)+(2*9)+(1*3)=234
234 % 10 = 4
So 879614-93-4 is a valid CAS Registry Number.
879614-93-4Relevant academic research and scientific papers
Synthesis and biological evaluation of novel benzamide derivatives as potent smoothened antagonists
Wu, Tian-Ming,Wang, Dao-Cai,Xiang, Pu,Zhang, Jian-Nan,Sang, Ya-Xiong,Lin, Hong-Jun,Chen, Jie,Xie, Gang,Song, Hang,Zhao, Ying-Lan,Xie, Yong-Mei
, p. 1426 - 1431 (2014/03/21)
A series of novel benzamide derivatives were prepared and evaluated using cell-based measurements. Among these compounds, 10f significantly inhibited Hedgehog signaling and showed equivalent or more potency than GDC-0449 in different tests. Furthermore, compound 10f potently inhibited the proliferation of Daoy, a medulloblastoma cell line that is reported to be resistant to GDC-0449, which indicated a promising prospect in the treatment of Hedgehog signaling pathway related cancer in clinical trial.
NOVEL IMIDAZOLIDINE DERIVATIVE AND USE THEREOF
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Page/Page column 57, (2010/11/27)
According to the present invention, a compound represented by formula (I): wherein Q is: A is a hydrogen atom, a halogen atom, -ORa or a C1-4 alkyl group which may be substituted by one or more halogen atoms; E is independently selected from a
