879688-27-4Relevant academic research and scientific papers
Aryl nucleoside H-phosphonates. Part 15: Synthesis, properties and, anti-HIV activity of aryl nucleoside 5′-α-hydroxyphosphonates
Szymanska, Agnieszka,Szymczak, Marzena,Boryski, Jerzy,Stawinski, Jacek,Kraszewski, Adam,Collu, Gabriella,Sanna, Giseppina,Giliberti, Gabriele,Loddo, Roberta,Colla, Paolo La
, p. 1924 - 1934 (2007/10/03)
Aryl nucleoside 5′-H-phosphonates 4 bearing AZT or 2′,3′-dideoxyuridine moieties were subjected to reaction with various aromatic aldehydes to produce nucleoside 5′-α- hydroxyphosphonate derivatives 2 as potential anti-HIV agents. Stability of the title c
One-pot synthesis of aryl phosphoramidate derivatives of AZT/d4T as anti-HIV prodrugs
Jiang, Peng,Guo, Xin,Fu, Hua,Jiang, Yuyang,Zhao, Yufen
, p. 2537 - 2539 (2007/10/03)
Arbuzov reaction of aryl phosphorodichloridite with mixture of one equivalent of AZT or d4T and one equivalent of tert-butyl alcohol led to the corresponding AZT/d4T aryl H-phosphonate diesters, and the following reaction of the H-phosphonate diesters wit
