879713-65-2

Usage

Uses

Used in Pharmaceutical Industry:
7-Bromo-1,1,2-trimethyl-1H-benzo[e]indole is used as a potential pharmaceutical compound for its unique chemical structure and properties. Its specific applications may include the development of new drugs or the enhancement of existing ones, given its potential reactivity with other substances and its distinct physical and chemical properties.
Used in Chemical Research:
7-Bromo-1,1,2-trimethyl-1H-benzo[e]indole is used as a research compound in the field of organic chemistry. Its unique structure and properties make it a valuable subject for studying the effects of different substituents on the overall characteristics of benzindole compounds, which can contribute to the advancement of chemical knowledge and the development of new compounds with specific applications.
Used in Material Science:
7-Bromo-1,1,2-trimethyl-1H-benzo[e]indole is used as a component in the development of new materials. Its unique properties, such as solubility and melting point, may be harnessed to create materials with specific characteristics, such as improved stability or enhanced reactivity, which can be applied in various industries.

InChI:InChI=1/C15H14BrN/c1-9-15(2,3)14-12-6-5-11(16)8-10(12)4-7-13(14)17-9/h4-8H,1-3H3

Upstream product

• 563-80-4 3-methyl-butan-2-one 

Relevant academic research and scientific papers

Polymethine dyes-loaded solid lipid nanoparticles (SLN) as promising photosensitizers for biomedical applications

Polymethine dyes (PMD) have proved to be excellent candidates in the biomedical field for potential applications in both diagnostic and therapeutic. However, PMD application in biomedicine is hindered by their poor solubility and stability in physiological conditions. Therefore, the incorporation of these dyes in nanosystems could be important to prevent the formation of dye aggregates in aqueous environment and to protect their photophysical characteristics. In the present work, two PMD based on the benzoindolenine ring (bromine benzo-cyanine-C4 and bromine benzo-squaraine-C4) were incorporated into Solid Lipid Nanoparticles (SLN) to solubilize and stabilize them in aqueous solutions. Obtained SLN showed a high incorporation efficiency for both PMD (≈90%) and not only preserved their spectroscopic properties in the NIR region even under physiological conditions but also improved them. Viability assays showed good biocompatibility of both empty and loaded nanocarriers while the cellular uptake and intracellular localization showed the effective internalization in MCF-7 cells, with a partial mitochondrial localization for CY-SLN. Moreover, in vitro phototoxicity assay showed that cyanine loaded-SLN (CY-SLN) is more photoactive than the free dye.

4,5-benzoindole compound and light-emitting application thereof

The invention provides a 4,5-benzoindole compound with a structural formula shown in the description. The 4,5-benzoindole compound has better thermal stability, high light emitting efficiency and highlight-emitting purity and can be applied to the fields of organic light-emitting devices, organic solar cells, perovskite batteries, organic thin-film transistors or organic light sensors. The invention also provides an organic light-emitting device. The device comprises an anode, a cathode and organic layers, the organic layers contain at least one layer of a light emitting layer, a hole injection layer, a hole transmission layer, an exciton barrier layer and an electronic transmission layer, and at least one layer of the organic layers contains the 4,5-benzoindole compound shown in a structural formula I. The organic light-emitting device prepared from the 4,5-benzoindole compound has the advantages of good light emitting efficiency, excellent color purity and long service life.