87976-03-2 Usage
Uses
Used in Pharmaceutical Industry:
Immethridine hydrochloride is used as a therapeutic agent for the treatment of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Its agonistic action on the histamine H3 receptor modulates neurotransmission and has been shown to have neuroprotective effects, potentially slowing down the progression of these diseases.
Additionally, Immethridine hydrochloride may be used in drug discovery and development as a research tool to study the role of histamine H3 receptors in various physiological and pathological processes. This can help in the identification of new drug targets and the development of novel therapeutic agents for a range of central nervous system disorders.
Biological Activity
Potent and highly selective histamine H 3 receptor agonist (pEC 50 = 9.74) that displays 300-fold selectivity over the H 4 receptor (pK i values are 9.07 and 6.61 respectively). Does not bind to H 1 or H 2 receptors at concentrations up to 10 μ M.
Check Digit Verification of cas no
The CAS Registry Mumber 87976-03-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,9,7 and 6 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 87976-03:
(7*8)+(6*7)+(5*9)+(4*7)+(3*6)+(2*0)+(1*3)=192
192 % 10 = 2
So 87976-03-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h1-4,6-7H,5H2,(H,11,12)
