879887-32-8

Basic information

• Product Name: 1-Boc-5-formylindoline
• Synonyms: 1-Boc-5-formylindoline;1H-Indole-1-carboxylicacid,5-forMyl-2,3-dihydro-,1,1-diMethylethylester;tert-butyl 5-formylindoline-1-carboxylate;5-Formyl-2,3-dihydro-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester
• CAS NO: 879887-32-8
• Molecular Formula: C₁₄H₁₇NO₃
• Molecular Weight: 247
• Mol File: 879887-32-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 382.1±41.0 °C(Predicted)
• Appearance: /
• Density: 1.186±0.06 g/cm3(Predicted)
• PKA: -2.49±0.20(Predicted)
• CAS DataBase Reference: 1-Boc-5-formylindoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Boc-5-formylindoline(879887-32-8)
• EPA Substance Registry System: 1-Boc-5-formylindoline(879887-32-8)

Safety Data

• Hazardous Substances Data: 879887-32-8(Hazardous Substances Data)

Usage

General Description

1-Boc-5-formylindoline is a chemical compound which is derived from indoline. The "1-Boc" in its name refers to the protected amine group attached to the indoline molecule. The "5-formyl" part indicates the presence of a formyl (CHO) group at the 5th position of the indoline ring. 1-Boc-5-formylindoline has potential applications in organic synthesis, especially in the formation of heterocyclic compounds. Its structure and reactivity make it valuable in the development of new materials, pharmaceuticals, and agrochemicals. Additionally, 1-Boc-5-formylindoline is of interest in the study of organic reactions and mechanisms due to its unique properties and usefulness in synthetic chemistry.

Upstream product

• 279256-09-6 1-(tert-butyloxycarbonyl)indole-5-carboxaldehyde 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1196-69-6 1H-indole-5-carboxaldehyde 
• 350683-41-9 1-Boc-5-hydroxymethylindoline 
• 261732-38-1 tert-butyl 5-bromoindoline-1-carboxylate 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1118649-53-8 5-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]-2,3-dihydro-1H-indole 
• 1118651-99-2 5-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]-N-ethyl-2,3-dihydro-1H-indol-1-carboxamide 
• 1187196-61-7 tert-butyl 5-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-isoxazol-3-yl]-2,3-dihydro-1H-indol-1-carboxylate 
• 957204-40-9 1-(tert-butoxycarbonyl)-5-[(E)-2-(4-phenyl-5-trifluormethyl-2-thienyl)ethenyl]indoline 

Relevant articles and documents

HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE

To provide a novel compound which has S1P receptor agonistic activity, exhibits excellent immunosuppressing effect, gives less adverse side effects, and can be orally administered. The invention provides a compound represented by general formula (I) (wherein A is a single bond, -O-, or - CH2-; R1 represents a hydrogen atom or a C1-C6 alkyl group, and V represents any one group selected from among the following groups (1) to (3) : (1) -G1-, (2) -G2-N(R2) -G3-, and (3) a group represented by formula 2, wherein each of Z1 and Z2 represents a hydrogen atom or a C1-C6 alkyl group, Z3 represents a hydrogen or the like, Q represents -CH2-O- or the like, and Y represents a group represented by foumula 3, a salt thereof, or a solvate thereof.

Sulfonamide bicyclic compounds

The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts and solvates, their pharmaceutical compositions, and their uses in inhibiting β-amyloid peptide (β-AP) production.