87996-54-1

Basic information

• Product Name: 2'-chloro-4-trifluoromethoxybenzophenone
• Synonyms: 2'-chloro-4-trifluoromethoxybenzophenone;(2-Chlorophenyl)[4-(trifluoromethoxy)phenyl]methanone;Einecs 289-366-2
• CAS NO: 87996-54-1
• Molecular Formula: C₁₄H₈ClF₃O₂
• Molecular Weight: 300.6603296
• EINECS: 289-366-2
• Mol File: 87996-54-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 342.6°Cat760mmHg
• Flash Point: 131.2°C
• Appearance: /
• Density: 1.367g/cm³
• CAS DataBase Reference: 2'-chloro-4-trifluoromethoxybenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-chloro-4-trifluoromethoxybenzophenone(87996-54-1)
• EPA Substance Registry System: 2'-chloro-4-trifluoromethoxybenzophenone(87996-54-1)

Safety Data

• Hazardous Substances Data: 87996-54-1(Hazardous Substances Data)

Upstream product

• 456-55-3 1-trifluoromethoxybenzene 
• 609-65-4 o-chlorobenzoyl chloride 

Relevant articles and documents

Acylation du trifluoromethoxybenzene en catalyse HF-BF3

Friedel and Crafts acylation of trifluoromethoxy- and trifluoromethyl-thiobenzene fails to give ketones in a one step synthesis if chlorinated Lewis acids (AlCl3) are used, because of halogen exchange on the -OCF3 and -SCF3 groups.The use of a fluorinated catalyst system such as HF-BF3 avoids exchange reactions and acylation occurs smoothly under mild conditions: - Low temperature and pressure - High yields (very often >90 percent) - Very high para-regioselectivity.Related reactions such as formylation or sulfonylation can also be achieved under similar conditions.