87999-04-0 Usage
Uses
Used in Organic Synthesis:
4-(5,6,7,8-Tetrahydro-naphthalen-2-yl)-thiazol-2-ylamine is used as a building block in organic synthesis for the creation of other organic molecules with similar structures. Its unique combination of a thiazole and tetrahydro-naphthalene rings provides a versatile platform for the development of new compounds with potential applications in various industries.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-(5,6,7,8-Tetrahydro-naphthalen-2-yl)-thiazol-2-ylamine is utilized as a key intermediate in the development of new drugs and pharmaceutical compounds. Its structural features make it a promising candidate for the synthesis of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Chemical Research:
4-(5,6,7,8-Tetrahydro-naphthalen-2-yl)-thiazol-2-ylamine also finds applications in chemical research, where it can be employed to study the properties and reactions of compounds containing thiazole and tetrahydro-naphthalene rings. This knowledge can contribute to the advancement of the chemical sciences and the discovery of new synthetic methods and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 87999-04-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,9,9 and 9 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 87999-04:
(7*8)+(6*7)+(5*9)+(4*9)+(3*9)+(2*0)+(1*4)=210
210 % 10 = 0
So 87999-04-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H14N2S/c14-13-15-12(8-16-13)11-6-5-9-3-1-2-4-10(9)7-11/h5-8H,1-4H2,(H2,14,15)
87999-04-0Relevant articles and documents
SUBSTITUTED PROPANAMIDES AS INHIBITORS OF NUCLEASES
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Page/Page column 11; 13; 23; 24; 30; 31, (2019/11/12)
The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
N-(4-Substituted-thiazolyl)oxamic Acid Derivatives, a New Series of Potent, Orally Actve Antiallergy Agents
Hargrave, Karl D.,Hess, Friedrich K.,Oliver, James T.
, p. 1158 - 1163 (2007/10/02)
A series of N-(4-substituted-thiazolyl)oxamic acid derivatives were synthesized and tested for antiallergy activity in the rat PCA model.These compounds were conveniently prepared by treatment of the appropriate acetophenone with thiourea and iodine or by reaction of the chloroacetylbenzene with thiourea to give the corresponding aminothiazoles; subsequent condensation with ethyloxalyl chloride gave the thiazolyloxamates.Many of the analogues showed a 50percent inhibition at oxamic acid ethanolamine salt (61, PRH-836-EA), has been selected for further pharmacological evaluation.