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4-(5,6,7,8-Tetrahydro-naphthalen-2-yl)-thiazol-2-ylamine is a chemical compound characterized by the presence of a thiazole ring fused to a tetrahydro-naphthalene ring. It has a molecular formula of C15H16N2S and a molar mass of 260.36 g/mol. 4-(5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-THIAZOL-2-YLAMINE is known for its potential applications in various scientific and industrial fields, particularly in organic synthesis and pharmaceutical research.

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  • 87999-04-0 Structure
  • Basic information

    1. Product Name: 4-(5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-THIAZOL-2-YLAMINE
    2. Synonyms: AURORA 22371;4-(5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-THIAZOL-2-YLAMINE;4-(5,6,7,8-TETRAHYDRO-2-NAPHTHALENYL)-1,3-THIAZOL-2-AMINE;4-(5,6,7,8-Tetrahydro-aphthalen-2-yl)thiazol-2-ylamine;2-Amino-4-(5,6,7,8-tetrahydro-2-naphthyl)thiazole 97%
    3. CAS NO:87999-04-0
    4. Molecular Formula: C13H14N2S
    5. Molecular Weight: 230.33
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 87999-04-0.mol
  • Chemical Properties

    1. Melting Point: 105-110℃
    2. Boiling Point: 435.3°C at 760 mmHg
    3. Flash Point: 217°C
    4. Appearance: /
    5. Density: 1.234g/cm3
    6. Vapor Pressure: 8.88E-08mmHg at 25°C
    7. Refractive Index: 1.653
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 4.53±0.10(Predicted)
    11. Sensitive: Moisture & Light Sensitive
    12. CAS DataBase Reference: 4-(5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-THIAZOL-2-YLAMINE(CAS DataBase Reference)
    13. NIST Chemistry Reference: 4-(5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-THIAZOL-2-YLAMINE(87999-04-0)
    14. EPA Substance Registry System: 4-(5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-THIAZOL-2-YLAMINE(87999-04-0)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 87999-04-0(Hazardous Substances Data)

87999-04-0 Usage

Uses

Used in Organic Synthesis:
4-(5,6,7,8-Tetrahydro-naphthalen-2-yl)-thiazol-2-ylamine is used as a building block in organic synthesis for the creation of other organic molecules with similar structures. Its unique combination of a thiazole and tetrahydro-naphthalene rings provides a versatile platform for the development of new compounds with potential applications in various industries.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-(5,6,7,8-Tetrahydro-naphthalen-2-yl)-thiazol-2-ylamine is utilized as a key intermediate in the development of new drugs and pharmaceutical compounds. Its structural features make it a promising candidate for the synthesis of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Chemical Research:
4-(5,6,7,8-Tetrahydro-naphthalen-2-yl)-thiazol-2-ylamine also finds applications in chemical research, where it can be employed to study the properties and reactions of compounds containing thiazole and tetrahydro-naphthalene rings. This knowledge can contribute to the advancement of the chemical sciences and the discovery of new synthetic methods and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 87999-04-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,9,9 and 9 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 87999-04:
(7*8)+(6*7)+(5*9)+(4*9)+(3*9)+(2*0)+(1*4)=210
210 % 10 = 0
So 87999-04-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H14N2S/c14-13-15-12(8-16-13)11-6-5-9-3-1-2-4-10(9)7-11/h5-8H,1-4H2,(H2,14,15)

87999-04-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
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  • Alfa Aesar

  • (H58317)  2-Amino-4-(5,6,7,8-tetrahydro-2-naphthyl)thiazole, 97%   

  • 87999-04-0

  • 5g

  • 1365.0CNY

  • Detail
  • Alfa Aesar

  • (H58317)  2-Amino-4-(5,6,7,8-tetrahydro-2-naphthyl)thiazole, 97%   

  • 87999-04-0

  • 25g

  • 5460.0CNY

  • Detail
  • Aldrich

  • (703311)  2-Amino-4-(5,6,7,8-tetrahydro-2-naphthyl)thiazole  97%

  • 87999-04-0

  • 703311-1G

  • 404.82CNY

  • Detail
  • Aldrich

  • (703311)  2-Amino-4-(5,6,7,8-tetrahydro-2-naphthyl)thiazole  97%

  • 87999-04-0

  • 703311-5G

  • 1,297.53CNY

  • Detail

87999-04-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-thiazol-2-amine

1.2 Other means of identification

Product number -
Other names F3099-5549

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:87999-04-0 SDS

87999-04-0Relevant articles and documents

SUBSTITUTED PROPANAMIDES AS INHIBITORS OF NUCLEASES

-

Page/Page column 11; 13; 23; 24; 30; 31, (2019/11/12)

The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

N-(4-Substituted-thiazolyl)oxamic Acid Derivatives, a New Series of Potent, Orally Actve Antiallergy Agents

Hargrave, Karl D.,Hess, Friedrich K.,Oliver, James T.

, p. 1158 - 1163 (2007/10/02)

A series of N-(4-substituted-thiazolyl)oxamic acid derivatives were synthesized and tested for antiallergy activity in the rat PCA model.These compounds were conveniently prepared by treatment of the appropriate acetophenone with thiourea and iodine or by reaction of the chloroacetylbenzene with thiourea to give the corresponding aminothiazoles; subsequent condensation with ethyloxalyl chloride gave the thiazolyloxamates.Many of the analogues showed a 50percent inhibition at oxamic acid ethanolamine salt (61, PRH-836-EA), has been selected for further pharmacological evaluation.

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