88012-58-2Relevant academic research and scientific papers
Colchicine glycorandomization influences cytotoxicity and mechanism of action
Ahmed, Aqeel,Peters, Noel R.,Fitzgerald, Megan K.,Watson Jr., James A.,Hoffmann, F. Michael,Thorson, Jon S.
, p. 14224 - 14225 (2006)
The reaction of 70 unprotected, diversely functionalized free reducing sugars with methoxyamine-appended colchicine led to the production of a 58-member glycorandomized library. High-throughput cytotoxicity assays revealed glycosylation to modulate specif
COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE
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Page/Page column 28, (2008/12/06)
Colchicine neoglycosides, method for their synthesis and methods for their use are disclosed. The invention provides analogs of colchicine glycosylated to include a sugar moiety on a colchicine scaffold that is generally unglycosylated in nature. The colc
AMIDINE COMPOUND AND HERBICIDE
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Page/Page column 21, (2010/11/30)
Novel amidine compounds which may be active ingredients in herbicides that are reliably effective at a lesser dose and highly safe, and herbicides containing these compounds as active ingredients are provided. Amidine compounds represented by a formula (1
