880158-85-0Relevant academic research and scientific papers
An improved aldehyde linker for the solid phase synthesis of hindered amides
Liley, Mark J.,Johnson, Tony,Gibson, Susan E.
, p. 1322 - 1329 (2006)
A novel aldehyde dual-linker system has been developed for the solid phase synthesis of sterically hindered amides. The linker [5-(4-formyl-3- hydroxyphenoxy)pentanoic acid] exploits an intramolecular oxygen-nitrogen acyl transfer mechanism to prepare com
