880253-79-2Relevant academic research and scientific papers
PPh3-Substituted[2,5-Ph2-3,4-Tol2(η 5-C4COH)]Ru(CO)(PPh3)H exhibits slower stoichiometric reduction, faster catalytic hydrogenation, and higher chemoselectivity for hydrogenation of aldehydes over ketones than the dicarbonyl Shvo catalyst
Casey, Charles P.,Strotman, Neil A.,Beetner, Sharon E.,Johnson, Jeffrey B.,Priebe, David C.,Guzei, Ilia A.
, p. 1236 - 1244 (2008/10/09)
The PPh3-substituted hydroxycyclopentadienyl ruthenium hydride [2,5-Ph2-3,4-Tol2(η5-C4COH)]- Ru(CO)(PPh3)H (1) stoichiometrically reduces aldehydes and ketones in the presence of a pyridine trap to produce alcohols and the ruthenium pyridine complex 5, with a rate law that is dependent only on [aldehyde] and [1]. The observation of deuterium kinetic isotope effects on substitution of the acidic and hydridic protons of 1 are consistent with concerted transfer of hydrogen to aldehydes during reduction. 1 catalytically hydrogenates aldehydes under mild temperature and pressure conditions. While the Shvo catalyst 2 shows little activity under these conditions, it surpasses 1 at elevated temperatures and pressures. 1 shows high chemoselectivity for catalytic hydrogenation of aldehydes over ketones, while 2 is much less selective.
