880360-25-8Relevant academic research and scientific papers
Improved stereoselectivity in intramolecular SN2′ cyclization through use of mechanistic principles
Woo, Duck Seo,Curtis-Long, Marcus J.,Seong, Hun Jeong,Tae, Hong Jun,Min, Suk Yang,Ki, Hun Park
, p. 209 - 214 (2007)
Valine and alanine were converted into the corresponding α-hydroxy-β-amino acids through intramolecular SN2′ cyclization. The novel cyclization protocol relied upon the use of N-benzyl-protected carbamates derived from α-amino acids. Georg Thie
Enantiospecific formation of 3,6-dihydro-1H-pyridin-2-ones: Low-pressure palladium-catalysed decarboxylative carbonylation of 3-tosyl-5-vinyloxazolidin- 2-ones
Knight, Julian G.,Lawson, Iain M.,Johnson, Christopher N.
, p. 227 - 230 (2007/10/03)
Palladium-catalysed decarboxylative carbonylation of 3-tosyl-5- vinyloxazolidin-2-ones 5 occurs at atmospheric pressure to give 1-tosyl-3,6-dihydro-1H-pyridin-2-ones 6. The reaction proceeds with no loss of enantiopurity and detosylation with sodium napht
