88055-38-3

Upstream product

• 89024-04-4 2,2-dimethyl-7-hydroxy-6-(3',4'-dimethoxy)benzoylacetyl-2H-chroman 
• 31273-58-2 1-(7-hydroxy-2,2-dimethylchroman-6-yl)ethanone 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Relevant academic research and scientific papers

Synthesis of Dihydropyranoflavonols by Modified Algar-Flynn-Oyamada Reaction

Modified Algar-Flynn-Oyamada reaction of substituted 3,4-dihydro-2H-1-benzopyrans (I-III) with 4-methoxybenzaldehyde, 3,4-methylenedioxybenzaldehyde and 3,4-dimethoxybenzaldehyde gives the dihydropyranoflavonols (IVa-c), (Va-c) and (VIa-c), respectively.

Performic Acid Oxidation of Dihydro-o-hydroxyaroylacetylbenzopyrans: A New Synthesis of Dihydropyranoflavonols and Their Dehydro Analogues

Performic acid oxidation of dihydro-o-hydroxyaroylacetylbenzopyrans (Ia-c and Va-c) in chloroform gives the dihydropyranoflavonols (IIa-c and VIa-c respectively).Methylation of IIa-b and VIa-b with dimethyl sulphate and aqueous sodium carbonate affords the corresponding dihydropyranomethoxyflavones (IIIa-b and VIIa-b) and benzylic bromination of IIIa-b and VIIa-b with N-bromosuccinimide followed by dehydrobromination with pyridine, affords the pyranomethoxyflavones (IVa-b and VIIIa-b respectively).