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88069-67-4

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88069-67-4 Usage

General Description

Pilsicainide is a class I antiarrhythmic drug that is used to treat cardiac arrhythmias, specifically paroxysmal atrial fibrillation. It works by inhibiting sodium channels in the heart, leading to a decrease in the conduction and excitability of cardiac tissue. This helps to prevent the rapid and irregular heartbeats associated with atrial fibrillation and restore normal heart rhythm. Pilsicainide is administered orally and has a relatively fast onset of action, making it useful for acute treatment of atrial fibrillation episodes. Like many antiarrhythmic drugs, pilsicainide can cause proarrhythmic effects and may require close monitoring of cardiac function during treatment. Overall, pilsicainide is an important option for managing atrial fibrillation and related arrhythmias.

Check Digit Verification of cas no

The CAS Registry Mumber 88069-67-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,0,6 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 88069-67:
(7*8)+(6*8)+(5*0)+(4*6)+(3*9)+(2*6)+(1*7)=174
174 % 10 = 4
So 88069-67-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H24N2O/c1-13-6-3-7-14(2)16(13)18-15(20)12-17-8-4-10-19(17)11-5-9-17/h3,6-7H,4-5,8-12H2,1-2H3,(H,18,20)

88069-67-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide

1.2 Other means of identification

Product number -
Other names Pilzicainide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:88069-67-4 SDS

88069-67-4Downstream Products

88069-67-4Relevant articles and documents

New Anthiarrythmic Agents. N-Aryl-8-pyrrolizidinealkanamides

Miyano, Seiji,Sumoto, Kunihiro,Satoh, Fumio,Shima, Keiyu,Hayashimatsu, Mariko,et al.

, p. 714 - 717 (2007/10/02)

The synthesis and antiarrhytmic activity of N-aryl-8-pyrrolizidinealkanamides are described.The targed compounds were evaluated for their ability to protect against chloroform-induced fibrillation in mice.Many of them were found to have antifibrillatory activity comparable to that of lidocaine; several are more potent than lidocaine.N-(2,6-Dimethylphenyl)-8-pyrrolizidineacetamide (6n), which was found to be more potent and less toxic (LD50) than lidocaine, also showed a long duration of action in dogs with venticular arrhythmias after oral administration.

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