88069-78-7

Upstream product

• 101246-06-4 2,3-diphenyl-1,1-dibromocyclopropane 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 33044-88-1 (3,3-dibromocyclopropane-1,2-diyl)dibenzene 
• 588-59-0 stilbene 
• 88074-10-6 C₁₅H₁₂Br₂ 

Downstream Products

• 5324-00-5 2,3-diphenyl-1H-indene 
• 1454309-49-9 3-phenyl-2-(o-tolyl)-1H-indene 
• 1454309-50-2 3-phenyl-2-(m-tolyl)-1H-indene 
• 1454309-51-3 3-phenyl-2-(p-tolyl)-1H-indene 
• 1454309-52-4 2-(3-methoxyphenyl)-3-phenyl-1H-indene 
• 1454309-53-5 3-phenyl-2-(phenylethynyl)-1H-indene 
• 1454309-54-6 3-(3-phenyl-1H-inden-2-yl)prop-2-yn-1-ol 
• 1961-96-2 1-phenyl-1H-indene 

Relevant academic research and scientific papers

THE CROSS COUPLING OF 2-BROMO-1-PHENYL INDENES WITH PHENYL ACETYLENES AND OTHER SUBSTITUTED ACETYLENES IN WATER

The cross-coupling reaction of 2-bromo-1 -phenyl indenes with phenyl acetylenes or propargyl alcohol is disclosed. The cross-coupling reaction uses a palladium catalyst with triphenylphosphine in the absence of a copper co-catalyst. The reaction is carrie

THE SYNTHESIS OF TETRAHYDROISOQUINOLINES FROM 2-METHYL-1-PHENYL SUBSTITUTED INDENES

A procedure for the synthesis of tetrahydroisoquinolines from 2-methyl-l -phenyl substituted indene is described. The process invovles the use of osmium tetroxide to cleave the indene double bond forming the keto aldehyde product, which is then combined w

PROCESS TO MAKE HIGHLY SUBSTITUTED INDENES USING METAL SLAT CATALYSTS

The present invention is a process to make l-aryl-2-bromo substituted indenes and l-phenyl-2-bromo substituted indenes that can have different functional groups present around the indene ring and/or the aromatic and/or phenyl ring. The indenes are made us

Synthesis of 2-bromo-1-aryl-1H-indenes via a Ag(I) promoted domino 2π-electrocyclic ring-opening/4π-electrocyclization reaction of 1,2-diaryl substituted gem-dibromocyclopropanes

2-Bromo-1-aryl substituted indenes can be synthesized from 1,2-diaryl substituted gem-dibromocyclopropanes via a domino reaction sequence. The cascade reaction involves silver(I) promoted ionization and 2π-disrotatory electrocyclic ring-opening, followed by a 4π-conrotatory electrocyclic ring closing reaction of the allylic carbocation intermediate. Reaction conditions utilize silver tetrafluoroborate (AgBF4) in dichloroethane at 65 C. Selectivity effects for the electrocyclization were also studied. The 2-bromoindenes can be further functionalized using cross-coupling reactions, such as the Suzuki-Miyaura protocol. The alkene π-bond of the indenes can also be isomerized to give the thermodynamically more stable 2-bromo-3-aryl-1H-indene isomers using triethylamine in dichloromethane at room temperature.

THERMAL TRANSFORMATIONS OF GEM-DIHALOGENODIPHENYLCYCLOPROPANES

When gem-dihalogenodiphenylcyclopropanes are heated, 2-halogenophenylindenes or diphenyl-2-halogeno-1,3-alkadienes are formed.The yields of the substituted indenes are increased in the presence of acidic catalysts, while the yield of the dienes is increas