88088-83-9Relevant academic research and scientific papers
Phosphocholine-substituted 5,10,15,20-Tetraphenylporphyrinatoiron(II): Oxygen Carrier under Physiological Conditions
Tsuchida, Eishun,Nishide, Hiroyuki,Yuasa, Makoto,Hasegawa, Etsuo,Matsushita, Yoh-ichi,Eshima, Kiyoshi
, p. 275 - 278 (2007/10/02)
A novel and amphiphilic 5,10,15,20-tetraphenylporphyrinatoiron complex substituted with phosphocholine groups, 5,10,15,20-tetraphenyl>porphyrinatoiron(II) (lipid-heme), has been synthesized.The lipid-heme formed a stable liposome with a phospholipid.The liposomal lipid-heme reversibly bound oxygen in neutral aqueous media at 37 deg C, and its oxygen-binding rate and affinity were similar to those of red blood cells.
SYNTHESIS OF AMPHIPHILIC PORPHINATO IRON COMPLEXES HAVING PHOSPHORYLCHOLINE GROUPS
Matsushita, Yoh-ichi,Hasegawa, Etsuo,Eshima, Kiyoshi,Tsuchida, Eishun
, p. 1387 - 1390 (2007/10/02)
New porphyrin derivatives having alkyl phosphorylcholine groups as amphiphilic moieties and their iron complexes were prepared.Based on the hydrophobic-hydrophilic balance, some of the synthesized complexes were efficiently embedded in the bilayer of phos
