88089-23-0Relevant academic research and scientific papers
THE PRODUCT FROM THE REACTION OF DIAZOMETHANE WITH 1,3-OXASELENOLE DERIVED FROM DIMEDONE
Matoba, Katsuhide,Yamazaki, Takao
, p. 1959 - 1962 (2007/10/02)
The 1,3-oxaselenole derivative (VI) obtained from dimedone was treated with an excess of diazomethane to give 1,4,7-dioxaselenocine derivative (VII) in a quantitative yield.The deselenization of VII was carried out by the benzyne-hydrogenolysis method to give 3-methoxy-5,5-dimethyl-2-(5,5-dimethyl-3-oxo-1-cyclohexen-1-yl)oxy-2-cyclohexenone (VIII).Treatment of VII with aqueous alkali gave 5,5,5',5'-tetramethyl-1,1',3,3'-tetroxo-2,2'-cyclohexylmethane (IX), and it afforded 4,4'-dibromo-3,3-dimethoxy-5,5-dimethylcyclohexanone (X) with bromine in MeOH.VII was reduced sodium borohydride to an allyl alcohol (XIa) which was converted to its acetate (XIb).
