88091-10-5Relevant academic research and scientific papers
Substrate- and base-dependent reactivities of acylketene toward aryl aldimines derived from 2-amino-4-methylpyridine
Ocal, Nuket,Mor, Necla,Erden, Ihsan
, p. 6468 - 6471 (2015/11/16)
Acylketene, generated from 2,2,6-trimethyl-4H-1,3-dioxin-4-one reacts with aryl aldimines derived from 4-methyl-2-aminopyridine to give a variety of products, depending on the substituent on the C-aryl group, base used, and hydrolytic stability of the starting aldimine. Also the presence of the N-(2-pyridyl) group plays an important role in the fate of the reaction course, frequently participating in intramolecular conjugate additions, giving rise to interesting heterocycles.
Reaction of 2,2,6-trimethyl-1,3-dioxin-4-one with Imines
Masayuki, Sato,Ogasawara, Hiromichi,Yoshizumi, Eriko,Kato, Tetsuzo
, p. 1902 - 1909 (2007/10/02)
The reaction of 2,2,6-trimethyl-1,3-dioxin-4-one (diketene-acetone adduct) (1) with imines was investigated.Heating of the adduct 1 with N-(1-phenylethylidene)aniline (6a) gave 6-methyl-1,2-diphenyl-4(1H)-pyridone 7a.Similar treatment of N-benzylideneanil
