88112-01-0Relevant academic research and scientific papers
Unusual Friedel-Crafts Reactions. Part 7. Synthesis of α-(2-Hydroxyphenyl)ethyl Lactates and Their Reductive Cyclization to 3-Methyl-2,3-dihydrobenzofuran-2-ols
Casiraghi, Giovanni,Sartori, Giovanni,Casnati, Giuseppe,Bigi, Franca
, p. 1649 - 1651 (2007/10/02)
A mild procedure has been developed where α-(2-hydroxyphenyl)ethyl lactates (3), obtained via aluminium trichloride-promoted ortho-specific alkylation of lithium phenolates (1) with ethyl pyruvate (2), are reductively cyclized to racemic 3-methyl-2,3-dihy
