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6,7-difluoro-2,3-dihydro-1H-inden-1-one is a chemical compound characterized by its molecular formula C9H6F2O, a white solid appearance, and a molecular weight of 174.14 g/mol. It features a fluoro-substituted indenone ring, which endows it with versatility as a starting material in organic synthesis and pharmaceutical research. Known for its potential biological activities and good stability, it is a popular choice for chemical reactions in laboratory settings.

881190-18-7

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881190-18-7 Usage

Uses

Used in Organic Synthesis:
6,7-difluoro-2,3-dihydro-1H-inden-1-one is used as a building block in organic synthesis for its ability to serve as a versatile starting material for the creation of various organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 6,7-difluoro-2,3-dihydro-1H-inden-1-one is utilized as a key intermediate in the development of new drugs due to its potential biological activities and its compatibility with other reagents and solvents, facilitating medicinal chemistry studies.
Used in Medicinal Chemistry Studies:
6,7-difluoro-2,3-dihydro-1H-inden-1-one is employed as a valuable target in medicinal chemistry for exploring its potential biological activities, which can lead to the discovery of new therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 881190-18-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,1,1,9 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 881190-18:
(8*8)+(7*8)+(6*1)+(5*1)+(4*9)+(3*0)+(2*1)+(1*8)=177
177 % 10 = 7
So 881190-18-7 is a valid CAS Registry Number.

881190-18-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6,7-Difluoro-1-indanone

1.2 Other means of identification

Product number -
Other names 6,7-difluoroindanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:881190-18-7 SDS

881190-18-7Downstream Products

881190-18-7Relevant articles and documents

SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS

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Page/Page column 24, (2008/12/04)

Therapeutic compounds, and methods, compositions, and medicaments related thereto are disclosed herein.

THERAPEUTIC FLUOROETHYLCYANO GUANIDINES

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Page/Page column 22, (2008/12/04)

Disclosed herein is compound having a formula as described herein. Therapeutic methods, compositions, and medicaments related thereto are also disclosed.

CYCLIC AMINE DERIVATIVE OR SALT THEREOF

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Page/Page column 24; 47, (2010/11/27)

Provided are compounds which are an NMDA antagonist having a broad safety margin and are useful as a treating agent or a preventing agent for Alzheimer's disease, cerebrovascular dementia, Parkinson's disease, ischemic apoplexy, pain, etc. Concretely prov

Indanylidenes. 1. Design and synthesis of (E)-2-(4,6-difluoro-1-indanylidene)acetamide, a potent, centrally acting muscle relaxant with antiinflammatory and analgesic activity

Musso, David L.,Cochran, Felicia R.,Kelley, James L.,McLean, Ed W.,Selph, Jeffrey L.,Rigdon, Greg C.,Orr, G. Faye,Davis, Ronda G.,Cooper, Barrett R.,Styles, Virgil L.,Thompson, James B.,Hall, William R.

, p. 399 - 408 (2007/10/03)

The design of rigid cyclic analogues derived from cinnamamide 1, (E)-N-cyclopropyl-3-(3-fluorophenyl)prop-2-enamide, and β-methylcinnamamide 2, (E)-N-cyclopropyl-3-(3-fluorophenyl)but-2-enamide, has led to the discovery of the potent, centrally acting muscle relaxant (E)-2-(4,6-difluoro-1-indanylidene)acetamide, 17. Compound 17 also possesses potent antiinflammatory and analgesic activity. This paper describes the synthesis and the muscle relaxant, antiinflammatory, and analgesic structure-activity relationships of 17 and 67 of its analogues. Compound 17 has been taken into phase I clinical trials.

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