88124-95-2

Upstream product

• 85-44-9 phthalic anhydride 
• 62595-52-2 undec-10-en-1-amine 
• 136918-14-4 phthalimide 
• 7766-50-9 1-undecen-11-ylbromide 
• 1074-82-4 potassium phtalimide 

Downstream Products

• 53179-04-7 undec-10-enenitrile 
• 1404456-85-4 C₃₁H₃₅N₃O₆S₃ 
• 1404456-96-7 C₂₅H₃₀N₂O₄S 
• 1374869-76-7 N,N'-(11-(1,3-dioxoisoindolin-2-yl)undecane-1,2-diyl)bis(4-methyl-N-tosylbenzenesulfonamide) 
• 183991-82-4 1-(O-acetylsalicyloylamino)undec-10-ene 

Relevant academic research and scientific papers

ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS

Compounds, methods of use, and processes for making inhibitors of complement Factor D comprising Formula I, or a pharmaceutically acceptable salt or composition thereof wherein R12 or R13 on the A group is an aryl, heteroaryl or heterocycle (R32) are provided. The inhibitors of Factor D described herein reduce the excessive activation of complement.

ALKYNE COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS

Compounds, methods of use, and processes for making inhibitors of complement Factor D are provided comprising Formula I, I" and I'" or a pharmaceutically acceptable salt or composition thereof. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade. The inhibitors of Factor D described herein reduce the excessive activation of complement.

FLUORESCENT LABELED INHIBITORS

Provided herein are a series of fluorescently labeled phosphonate and phosphate compounds such as can be used for affinity probes to detect certain enzymes including lipases. Also provided are methods of making and using such compounds.

Oligoamide duplexes as organogelators

Oligoamide duplexes carrying multiple alkyl side chains were found to serve as gelators for aromatic solvents. The double-stranded backbone was essential for the hierarchical self-assembly of the molecular duplex into fibers of high aspect ratios. The demonstrated gelating abilities may be extended to a large family of analogous H-bonded duplexes having different H-bonding sequences, leading to a unique platform for developing a diverse variety of potential gelators based on a supramolecular and/or a dynamic covalent approach.

Siloxanes with pendent naphthalene diimides: Synthesis and fluorescence quenching

Cyclic siloxanes with pendent naphthalene diimide groups were synthesized via hydrosilylation to form amorphous electron-accepting compounds. Photophysical measurements and >99.9% fluorescence quenching of well-known p-type polymers by the siloxanes demonstrate that these siloxanes form a new class of highly efficient n-type materials that provide some control over intermolecular interactions.