88129-14-0 Usage
Chemical Family
Pyrimidines
Enzyme Inhibition
Dihydrofolate reductase
Role in Synthesis
Essential for DNA synthesis and cell proliferation
Potential Applications
a. Antineoplastic agent
b. Antirheumatic agent
c. Anticancer activity
Activity Against
a. Methicillin-resistant Staphylococcus aureus (MRSA)
b. Other bacterial infections
Additional Potential
Photosensitizer in photodynamic therapy for cancer
Versatility
Various potential applications in medicine and biotechnology
Check Digit Verification of cas no
The CAS Registry Mumber 88129-14-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,1,2 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 88129-14:
(7*8)+(6*8)+(5*1)+(4*2)+(3*9)+(2*1)+(1*4)=150
150 % 10 = 0
So 88129-14-0 is a valid CAS Registry Number.
88129-14-0Relevant academic research and scientific papers
The Structure of Chalkone-Guanidine-Condensates. Heterocyclic Compounds, 75. Commun.
Wendelin, Winfried,Schermanz, Karl,Kerbl, Johannes
, p. 717 - 737 (2007/10/02)
Guanidine reacts with chalkone 1a, 4-methylchalkone 1b and 4'-methylchalkone 1c resp. to yield mixtures of pyrimidinamines 2a, 3b and 3c (=3b) resp. with (2:1)-condensates A, B and C resp.The structures of the compounds A-C(which a priori could be dihydro
