881398-66-9Relevant academic research and scientific papers
BF3·Et2O promoted selective synthesis of benzimidazoles
Rajanarendar,Ramesh,Kalyan Rao,Mohan,Siva Rami Reddy
, p. 1153 - 1159 (2008/04/12)
(Chemical Equation Presented) Benzimidazoles 3, 6 and 9 have been synthesized selectively in excellent yields by cyclocondensation of β-(3-methyl-5-styryl-4-isoxazolyl amido) benzoic acids, acrylic acids and propionic acids with 1,2-phenylene diamines by employing BF3· Et2O as the catalyst. When the same reaction was carried out in pyridine it resulted in mixture of products in each case (3 & 4, 6 & 7 and 9 & 10). Other methods tried by using polyphosphoric acid, HCl, TFA also led to mixtures of 3 & 4, 6 & 7 and 9 & 10 in each case, similar to that of pyridine reaction.
Synthesis 3-aryl-5-N-(3-methyl-5-styryl-4-isoxazolyl)-4,6-dioxopyrrolo[3,4-d]-7, 8-dihydroisoxazoles
Rajanarendar,Srinivas,Karunakar
, p. 1997 - 1999 (2007/10/03)
A series of cycloadducts, namely 3-aryl-5-N-(3-methyl-5-styryl4-isoxazolyl)-4,6-dioxopyrrolo[3,4-d] -7,8-dihydroisoxazoles 3a-h have been prepared by cycloaddition of benzonitrile oxides generated in situ with N-(3-methyl-5-styryl-4-isoxazolyl)maleimides
