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2-Fluoro-5-(trifluoromethoxy)phenylboronic acid is a boronic acid derivative featuring a fluorine and trifluoromethoxy group substitution on the phenyl ring. It is a versatile reagent in organic synthesis, playing a crucial role in the preparation of pharmaceuticals, agrochemicals, and materials. Its unique structure allows it to participate in various chemical reactions, making it an essential building block for the synthesis of complex organic molecules with diverse applications.

881402-22-8

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881402-22-8 Usage

Uses

Used in Organic Synthesis:
2-Fluoro-5-(trifluoromethoxy)phenylboronic acid is used as a reagent in organic synthesis for the preparation of various pharmaceuticals, agrochemicals, and materials. Its unique structure and reactivity enable the formation of carbon-carbon bonds, which are essential for constructing complex organic molecules.
Used in the Suzuki-Miyaura Cross-Coupling Reaction:
In the field of organic chemistry, 2-fluoro-5-(trifluoromethoxy)phenylboronic acid is used as a key component in the Suzuki-Miyaura cross-coupling reaction. This reaction is widely employed for the construction of carbon-carbon bonds, allowing the formation of a wide range of organic compounds with potential applications in various industries.
Used in Medicinal Chemistry and Drug Discovery:
2-Fluoro-5-(trifluoromethoxy)phenylboronic acid is used as a building block in medicinal chemistry and drug discovery. Its ability to modify the biological activity and pharmacokinetic properties of drug candidates makes it a valuable tool for the development of new therapeutic agents. By incorporating 2-FLUORO-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID into drug molecules, researchers can enhance the efficacy, selectivity, and pharmacokinetic profile of potential drugs.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-fluoro-5-(trifluoromethoxy)phenylboronic acid is used as a key intermediate in the synthesis of various drug molecules. Its unique structure and reactivity contribute to the development of innovative therapeutic agents with improved potency, selectivity, and pharmacokinetic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 2-fluoro-5-(trifluoromethoxy)phenylboronic acid is used as a building block for the synthesis of various agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness, selectivity, and environmental compatibility.
Overall, 2-fluoro-5-(trifluoromethoxy)phenylboronic acid is a versatile and valuable compound in the fields of organic synthesis, medicinal chemistry, and various industries, including pharmaceuticals and agrochemicals. Its unique structure and reactivity make it an essential component in the development of innovative and effective products.

Check Digit Verification of cas no

The CAS Registry Mumber 881402-22-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,1,4,0 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 881402-22:
(8*8)+(7*8)+(6*1)+(5*4)+(4*0)+(3*2)+(2*2)+(1*2)=158
158 % 10 = 8
So 881402-22-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H5BF4O3/c9-6-2-1-4(15-7(10,11)12)3-5(6)8(13)14/h1-3,13-14H

881402-22-8 Well-known Company Product Price

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  • Alfa Aesar

  • (H52449)  2-Fluoro-5-(trifluoromethoxy)benzeneboronic acid, 97%   

  • 881402-22-8

  • 250mg

  • 662.0CNY

  • Detail
  • Alfa Aesar

  • (H52449)  2-Fluoro-5-(trifluoromethoxy)benzeneboronic acid, 97%   

  • 881402-22-8

  • 1g

  • 2117.0CNY

  • Detail

881402-22-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-fluoro-5-(trifluoromethoxy)phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:881402-22-8 SDS

881402-22-8Upstream product

881402-22-8Relevant academic research and scientific papers

PYRIDINE DERIVATIVES

-

Page/Page column 159; 160, (2009/01/20)

The present invention relates to compounds of the formula (I): (I) and pharmaceutically acceptable salts and solvates thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds for the treatment of pain.

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