88141-39-3Relevant academic research and scientific papers
Synthesis of chiral seven-membered β-substituted lactams: Via Rh-catalyzed asymmetric hydrogenation
Huang, Yi,Li, Pan,Dong, Xiu-Qin,Zhang, Xumu
supporting information, p. 8819 - 8823 (2018/11/30)
Rh/bisphosphine-thiourea ligand (ZhaoPhos)-catalyzed asymmetric hydrogenation of seven-membered β-substituted α,β-unsaturated lactams was successfully developed to prepare various chiral seven-membered β-substituted lactams with good to excellent results (up to >99% conversion, 99% yield, and >99% ee).
Synthesis of 3-aryl-6-aminocyclohex-2-enol derivatives
Itoh,Oka
, p. 2016 - 2022 (2007/10/02)
6-(N-Substituted amino)-3-arylcyclohex-2-enol was designed as a new type of β-adrenergic blocker on the basis of the X-ray crystallographic data for propranolol. Eight such compounds were prepared by a six-step sequence of reactions from 3-aryl-cyclohex-2
