88141-88-2

Basic information

• Product Name: N,N-dimethylamino-3-guaiazulenylmethane
• CAS NO: 88141-88-2
• Molecular Weight: 255.403
• Mol File: 88141-88-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N-dimethylamino-3-guaiazulenylmethane(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethylamino-3-guaiazulenylmethane(88141-88-2)
• EPA Substance Registry System: N,N-dimethylamino-3-guaiazulenylmethane(88141-88-2)

Safety Data

• Hazardous Substances Data: 88141-88-2(Hazardous Substances Data)

Upstream product

• 489-84-9 7-isopropyl-1,4-dimethyl-azulene 
• 33797-51-2 eschenmoser's salt 
• 100-61-8 N-methylaniline 

Relevant articles and documents

Synthesis of 2-(4-azulenyl)ethanamine derivatives as a nonbenzenoid analog of biogenic amine

2-(4-Azulenyl)ethanamine derivatives, nonbenzenoid analogs of the biologically active amine, were synthesized by the action of methyleneammonium salts on sodium 4-methylazulenide, sodium 4,6,8-trimethylazulenide, and sodium guaiazulenide. These compounds, as well as their hydrochlorides, were characterized by UV, IR, **1H NMR, **1**3C NMR, and MS data. The reaction of sodium guaiazulenide and N-ethylidenemethylamine also yielded the corresponding 2-(4-azulenyl)ethanamine derivatives, but the low yield of the product showed that the electrophilicity of azomethine carbon atom to 4-methylene carbanion was insufficient. The enzyme activity for some of those products was investigated. Negligible effect was found on prostaglandin 15-hydroxydehydrogenase, and considerable inhibition to cyclic AMP-phosphodiesterase, in vitro.