881423-80-9

Upstream product

• 108-24-7 acetic anhydride 
• 583-53-9 2,3-dibromobenzene 
• 130222-84-3 5-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribono-1,4-lactone 
• 881423-76-3 1-(2-bromophenyl)-5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose 

Downstream Products

• 881424-10-8 acetic acid 5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-6a-(2-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-hexahydro-furo[3,2-b]furan-3-yl ester 
• 881424-01-7 acetic acid 6a-(2-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester 
• 881424-02-8 1-[(1R,3S,5S,7R,8R)-5-(2-bromophenyl)-8-hydroxy-7-(hydroxymethyl)-2,6-dioxabicyclo[3.3.0]octan-3-yl]thymine 

Relevant academic research and scientific papers

Effects of halogenated WNA derivatives on sequence dependency for expansion of recognition sequences in non-natural-type triplexes

Triplex-forming oligonucleotides (TFOs) are sequence-specific DNA-binding agents, but their target duplexes are limited to homopurine/homopyrimidine sequences because of interruption of the pyrimidines bases in the purine region. This problem has not been