881658-52-2Relevant academic research and scientific papers
Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity
Surivet, Jean-Philippe,Zumbrunn, Cornelia,Rueedi, Georg,Hubschwerlen, Christian,Bur, Daniel,Bruyère, Thierry,Locher, Hans,Ritz, Daniel,Keck, Wolfgang,Seiler, Peter,Kohl, Christopher,Gauvin, Jean-Christophe,Mirre, Azely,Kaegi, Verena,Dos Santos, Marina,Gaertner, Mika,Delers, Jonathan,Enderlin-Paput, Michel,Boehme, Maria
, p. 7396 - 7415 (2013/10/21)
There is an urgent need for new antibacterial drugs that are effective against infections caused by multidrug-resistant pathogens. Novel nonfluoroquinolone inhibitors of bacterial type II topoisomerases (DNA gyrase and topoisomerase IV) have the potential
TETRAHYDROPYRANE ANTIBIOTICS
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Page/Page column 75, (2010/11/28)
The invention relates to antibiotic tetrahydro rane derivatives of formula (I).
ANTIBIOTIC COMPOUNDS
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Page/Page column 28, (2010/11/28)
The invention relates to selected antibiotics of formula (Al) wherein R1 represents alkyl, alkoxy, haloalkoxy, halogen or cyano; one or two of U, V, W and X represent(s) N, the remaining represent CH, or, in case of U, V and/or W, may also repr
ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES
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Page/Page column 44, (2008/06/13)
The invention relates to antibiotic ethanol or 1,2-ethanediol cyclohexyl derivatives of formula (I) wherein R1 represents (C1-C4)alkoxy; one or two of U, V, W and X represent(s) N and the remaining represent each independently CH or, in the case of V or X
