881668-59-3 Usage
Heterocyclic organic compound
contains a pyrazole ring fused to a pyridine ring
Potent inhibitor of enzymes
cyclin-dependent kinase 8 (CDK8) and cyclin-dependent kinase 19 (CDK19)
Promising candidate for cancer treatment
Valuable tool for medicinal chemistry research and drug development
due to the presence of 3,4-dichlorophenyl and 4-methoxyphenyl substituents on the pyrazole ring.
Check Digit Verification of cas no
The CAS Registry Mumber 881668-59-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,1,6,6 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 881668-59:
(8*8)+(7*8)+(6*1)+(5*6)+(4*6)+(3*8)+(2*5)+(1*9)=223
223 % 10 = 3
So 881668-59-3 is a valid CAS Registry Number.
881668-59-3Relevant academic research and scientific papers
An efficient synthesis of pyrazolo[3,4-b]pyridine derivatives in ionic liquid
Shi, Da-Qing,Zhou, Yao,Liu, Hai
experimental part, p. 3660 - 3668 (2011/02/27)
A series of 3-methyl-1,4,6-triaryl-1H-pyrazolo[3,4-b]pyridines was synthesized via the reaction of 3-methyl-1-phenyl-1H-pyrazol-5-amine and,-unsaturated ketones in ionic liquid without any catalyst. This protocol has the advantages of easier work-up, milder reaction conditions, high yields and environmentally benign procedure. Copyright
