881672-80-6Relevant academic research and scientific papers
Facile synthesis of pyrido[1,2-a]benzimidazole derivatives via novel tandem reaction involving horner-emmons reaction
Zhao, Wen-Jing,Xie, Ya-Fei,Ge, Yan-Qing,Xu, Wei-Ren,Zhao, Gui-Long,Wang, Jian-Wu
, p. 1121 - 1126 (2013/05/23)
Pyrido[1,2-a]benzimidazole derivatives were conveniently synthesized by a novel tandem reaction under mild conditions. The reaction mechanism was also proposed.
The synthesis, characterization and optical properties of novel pyrido[1,2-a]benzimidazole derivatives
Ge, Yan Qing,Jia, Jiong,Yang, He,Tao, Xu Tang,Wang, Jian Wu
experimental part, p. 344 - 349 (2011/06/11)
A series of novel, substituted, pyrido[1,2-a]benzimidazole derivatives were synthesized using a novel tandem annulation reaction between 2-acylbenzimidazole derivatives and 4-bromobut-2-enoic esters under mild conditions. The compounds were characterized using IR, 1H NMR, 13C NMR and HRMS; the crystal structure of 2,7,8-trimethyl-3- ethoxycarbonyl-4-phenylpyrido[1,2-a]benzimidazole was determined as orthorhombic. The absorbance and fluorescence spectra of the pyrido[1,2-a]benzimidazoles were measured in dichloromethane; an intense absorption maxima was observed at 250 nm and emission maxima were noted at 460 nm. The absorption spectra and fluorescence characteristics of the pyrido[1,2-a]benzimidazole derivatives revealed that a phenyl and a methyl group attached to the pyrido[1,2-a]benzimidazole ring markedly influenced maximum emission.
