881673-64-9

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Molecular Structure

1H-Pyrrole-3-carboxaldehyde, 5-(4-fluorophenyl)-1-[[4-(trifluoromethyl)phenyl]sulfonyl]is a complex organic compound that consists of a pyrrole ring, a carboxaldehyde group, a sulfonyl group, a 4-fluorophenyl group, and a trifluoromethylphenyl group.

Pyrrole Ring

The compound contains a pyrrole ring, which is a five-membered aromatic ring with one nitrogen atom and four carbon atoms. The nitrogen atom contributes to the ring's electron density, making it electron-rich and reactive.

Carboxaldehyde Group

The carboxaldehyde group (-CHO) is a functional group consisting of a carbonyl group (C=O) bonded to a hydrogen atom and an alkyl or aryl group. It is polar and can form hydrogen bonds, making it reactive in various chemical reactions.

Sulfonyl Group

The sulfonyl group (-SO2-) is a functional group consisting of a sulfur atom double-bonded to two oxygen atoms. It is electronegative and can influence the reactivity of nearby functional groups.

4-Fluorophenyl Group

The 4-fluorophenyl group is an aromatic ring with a fluorine atom attached to the 4-position. The presence of the electronegative fluorine atom can affect the reactivity and properties of the compound.

Trifluoromethylphenyl Group

The trifluoromethylphenyl group is an aromatic ring with a trifluoromethyl group (-CF3) attached. The electronegative fluorine atoms in the trifluoromethyl group can influence the compound's reactivity and properties.

Complexity

The compound's complex structure, with multiple functional groups and electronegative atoms, can lead to various chemical reactions and properties. Researchers and chemists may study these properties to find potential applications in industry or scientific research.

Industrial and Research Applications

Due to its unique structure, 1H-Pyrrole-3-carboxaldehyde, 5-(4-fluorophenyl)-1-[[4-(trifluoromethyl)phenyl]sulfonyl]may have various industrial or research applications. Further study of its properties and potential uses can lead to new discoveries and applications in different fields.

Upstream product

• 881673-57-0 ethyl 5-(4-fluorophenyl)-1-{[4-(trifluoromethyl)phenyl]sulfonyl}-1H-pyrrole-3-carboxylate 

Relevant academic research and scientific papers

Proton pump inhibitors

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R 1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R 2 , R 3 and R 4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R 5 and R 6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.

PROTON PUMP INHIBITORS

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R2, R3 and R4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R5 and R6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.

PROTON PUMP INHIBITORS

Proton pump inhibitors which have excellent proton pumping activity and which can be converted in vivo into proton pump inhibitors to exhibit antiulcer effect and so on, containing compounds represented by the general formula (I) or salts thereof or prodrugs of the same: (I) wherein X and Y are each independently a free valency or a spacer whose main chain has 1 to 20 carbon atoms; R1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; R2, R3 and R4 are each independently hydrogen, an optionally substituted hydrocarbon group, optionally substituted thienyl, optionally substituted benzo[b]thienyl, optionally substituted furyl, optionally substituted pyridyl, optionally substituted pyrazolyl, optionally substituted pyrimidinyl, acyl, halogeno, cyano, or nitro; and R5 and R6 are each independently hydrogen or an optionally substituted hydrocarbon group.