881687-20-3

Upstream product

• 1193-21-1 4,6-dichloropyrimidine 
• 867314-22-5 2-[(4-{[(furan-2-ylmethyl)amino]methyl}phenyl)thio]-2-methyl-propionic acid tert-butylester hydrochloride 

Downstream Products

• 881687-30-5 tert-butyl-2-({4-[((2-furylmethyl){6-[3-chlorophenyl]pyrimidin-4-yl}amino)methyl]-phenyl}thio)-2-methylpropanoate 
• 881687-32-7 tert-butyl-2-[(4-{[[6-(4-fluoro-3-methylphenyl)pyrimidin-4-yl](2-furylmethyl)amino]methyl}-phenyl)thio]-2-methylpropanoate 
• 881687-24-7 tert-butyl-2-{[4-({(2-furylmethyl)[6-(4-methylbenzyl)pyrimidin-4-yl]amino}methyl)phenyl]thio}-2-methylpropanoate 
• 881687-23-6 tert-butyl-2-{[4-({(2-furylmethyl)[6-(3-methylbenzyl)pyrimidin-4-yl]amino}methyl)phenyl]thio}-2-methylpropanoate 
• 881687-41-8 tert-butyl-2-{[4-({(2-furylmethyl)[6-(4-methylphenoxy)pyrimidin-4-yl]amino}methyl)phenyl]-thio}-2-methylpropanoate 
• 881687-29-2 tert-butyl-2-({4-[((2-furylmethyl){6-[3-(trifluoromethyl)phenyl]pyrimidin-4-yl}amino)methyl]-phenyl}thio)-2-methylpropanoate 
• 881687-31-6 tert-butyl-2-methyl-2-{[4-({[6-(3-methylphenyl)pyrimidin-4-yl]amino}methyl)-phenyl]thio}-2-methylpropanoate 

Relevant academic research and scientific papers

NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE AS PPAR-ALPHA MODULATORS

The invention relates to novel pyrimidine derivatives of general formula (I), methods for the production thereof, their use for treating and/or preventing diseases, and to their use for producing medicaments for treating and/or preventing diseases, preferably for treating and/or preventing cardiovascular diseases, particularly dyslipidemia, arteriosclerosis, insufficiency of the heart, thrombosis and metabolic syndrome.