881691-88-9Relevant articles and documents
Click chemistry as a route to cyclic tetrapeptide analogues: Synthesis of cyclo-[Pro-Val-ψ(triazole)-Pro-Tyr]
Bock, Victoria D.,Perciaccante, Rossana,Jansen, T. Paul,Hiemstra, Henk,Van Maarseveen, Jan H.
, p. 919 - 922 (2006)
Despite the plethora of techniques to cyclize small peptides, a synthesis of cyclo-[(L)Pro-(L)Tyr-(L)Pro-(L)Val], a potent tyrosinase inhibitor, remains elusive because of the unfavorable transition state leading to the cyclic product. Herein, we report t