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CAS

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88182-33-6

Levistilide A, a natural chemical compound derived from the roots of the traditional Chinese medicinal plant Ligusticum chuanxiong, is a member of the phthalides class. Identified as an active ingredient, it is responsible for the plant's pharmacological effects. With its potential therapeutic properties, including anti-inflammatory, neuroprotective, and cardiovascular protective activities, Levistilide A has emerged as a promising drug candidate for the treatment of neurological and cardiovascular diseases. Further research is essential to fully comprehend its pharmacological effects and potential applications.

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  • 88182-33-6 Structure

  • Basic information

    1. Product Name: Levistilide A
    2. Synonyms: Levistilide A;(1Z,5S,5aS,8Z,10bS,10cS)-1,8-Dibutylidene-5,5a,6,7,8,10b-hexahydro-1H-5,10c-ethanonaphtho[1,2-c:7,8-c']difuran-3,10-dione;Diligustilide;Levistolid A;Levistolide A;Z,Z'-6,6',7,3'a-Diligustilide;Levistilide A, 98%, from Angelica sinensis (Oliv.) Diels
    3. CAS NO:88182-33-6
    4. Molecular Formula: C24H28O4
    5. Molecular Weight: 380.47672
    6. EINECS: N/A
    7. Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
    8. Mol File: 88182-33-6.mol

  • Chemical Properties

    1. Melting Point: 112-114 °C
    2. Boiling Point: 623.8±55.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.23
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: Levistilide A(CAS DataBase Reference)
    10. NIST Chemistry Reference: Levistilide A(88182-33-6)
    11. EPA Substance Registry System: Levistilide A(88182-33-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: 24/25
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 88182-33-6(Hazardous Substances Data)

88182-33-6 Usage

Uses

Used in Pharmaceutical Industry:
Levistilide A is used as a therapeutic agent for its anti-inflammatory properties, which can help in reducing inflammation in various conditions.
Levistilide A is used as a neuroprotective agent for its potential to protect the nervous system and treat neurological disorders.
Levistilide A is used as a cardiovascular protective agent for its potential to safeguard the heart and blood vessels, contributing to the prevention and treatment of cardiovascular diseases.
While the provided materials do not explicitly list the uses of Levistilide A in different industries, the primary focus is on its potential applications in the pharmaceutical industry for therapeutic purposes. Further research and development may reveal additional applications in other industries.

Check Digit Verification of cas no

The CAS Registry Mumber 88182-33-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,1,8 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 88182-33:
(7*8)+(6*8)+(5*1)+(4*8)+(3*2)+(2*3)+(1*3)=156
156 % 10 = 6
So 88182-33-6 is a valid CAS Registry Number.

88182-33-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name levistolide A

1.2 Other means of identification

Product number -
Other names diligustilide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:88182-33-6 SDS

88182-33-6Upstream product

88182-33-6Downstream Products

88182-33-6Relevant articles and documents

Chemical reactivity of phthalides. Relay synthesis of diligustilide, rel-(3'R)-3',8'-dihydrodiligustilide and wallichilide

Rios, Maria Yolanda,Delgado, Guillermo,Toscane, Ruben A.

, p. 3355 - 3366 (2007/10/03)

Diels Alder reaction using Z-ligustilide (3) both as diene and dienophile afforded the natural product diligustilide (1). The relay synthesis of 5 from 1 (via situ-selective lactone ring opening, reduction with NaBH4/MeOH and lactonization with SOCl2/THF) was achieved and confirmed the revised structure of 5, a secondary constituent of Ligusticum wallichii. The natural substance wallichilide (8) was also obtained directly from 1.

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