881830-06-4

Upstream product

• 258532-81-9 8-acetoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazine 
• 258532-76-2 8-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazine 
• 258532-84-2 8-acetoxy-4-(4,4-diphenylpentyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine 
• 881830-13-3 toluene-4-sulfonic acid 4,4-diphenyl-pentyl ester 

Downstream Products

• 258532-89-7 4-(4,4-diphenylpentyl)-8-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazine 

Relevant academic research and scientific papers

Development of 3,4-dihydro-2H-benzo[1,4]oxazine derivatives as dual thromboxane A2 receptor antagonists and prostacyclin receptor agonists

We discovered a novel series of 3,4-dihydro-2H-benzo[1,4]oxazin-8- yloxyacetic acid derivatives as potent dual-acting agents to block the TXA 2 receptor and to activate the PGI2 receptor. We report the synthesis, structure-activity r