88199-67-1 Usage
Chemical class
Nitrogen mustard alkylating agent
Functionality
Forms covalent bonds with nucleophilic functional groups in DNA and proteins
Cytotoxic effects
Leads to cell death
Potential use
Antitumor agent
Cancer treatment
Studied for use in various types of cancer
Limitations
High toxicity and potential for adverse effects on normal tissue
Clinical use
Limited due to toxicity and side effects
Hazardous chemical
Requires careful handling and safety precautions
Check Digit Verification of cas no
The CAS Registry Mumber 88199-67-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,1,9 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 88199-67:
(7*8)+(6*8)+(5*1)+(4*9)+(3*9)+(2*6)+(1*7)=191
191 % 10 = 1
So 88199-67-1 is a valid CAS Registry Number.
88199-67-1Relevant articles and documents
Steroids and Related Studies: Part LXI - N-(2-Chloroethyl)-nucleoazasteroids
Singh, Harkishan,Kumar, Vijay,Paul, Daram
, p. 1181 - 1183 (2007/10/02)
The nitrogen mustard-type nucleoazasteroids, 4-(2-chloroethyl)-4-aza-5α-cholestane (3), 4-(2-chloroethyl)-4-aza-5α-androstan-17β-ol (6), 3β-chloro-17a-(2-chloroethyl)-17a-aza-D-homo-5-androstene (9), and 4,17a-di-(2-chloroethyl)-4,17a-diaza-D-homo-5α-androstane (12) have been prepared as potential antineoplastic agents.Compound HS-479 (6) shows some activity against P388 leukaemia.
