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1-[4-(trifluoromethyl)phenyl]propan-2-amine is an organic compound with the molecular formula C10H12F3N. It is a derivative of propan-2-amine, featuring a trifluoromethyl-phenyl group attached to the nitrogen atom. This chemical is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals, particularly as a building block for the development of new compounds with specific biological activities. The presence of the trifluoromethyl group can significantly influence the compound's lipophilicity and metabolic stability, which are important factors in drug design. The compound is typically synthesized through various chemical reactions and can be further functionalized to create a range of derivatives with different properties and applications.

882-00-8

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882-00-8 Usage

Classification

Synthetic drug, substituted phenethylamine

Derivative of

Cathinone

Structural relation

Amphetamine

Action

Releasing agent of serotonin, dopamine, and norepinephrine

Effects

Increased energy and alertness, improved mood, heightened sociability

Recreational use

Euphoric and empathogenic properties

Risks

Increased heart rate and blood pressure, anxiety, insomnia, potential addiction

Legal status

Schedule I controlled substance in the United States

Reasons for legal status

Abuse potential and lack of recognized medical use

Check Digit Verification of cas no

The CAS Registry Mumber 882-00-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,8 and 2 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 882-00:
(5*8)+(4*8)+(3*2)+(2*0)+(1*0)=78
78 % 10 = 8
So 882-00-8 is a valid CAS Registry Number.

882-00-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[4-(trifluoromethyl)phenyl]propan-2-amine,hydrochloride

1.2 Other means of identification

Product number -
Other names P-1727

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:882-00-8 SDS

882-00-8Upstream product

882-00-8Relevant academic research and scientific papers

Method of treating nausea and vomiting with certain substituted-phenylalkylamino (and aminoacid) derivatives and other serotonin depleting agents

-

, (2008/06/13)

A method for the treatment of emesis in a mammal, which method comprises administering to said mammal an emesis inhibiting amount of a compound which depletes serotonin in the brain of mammals; among which are compounds having the formula: STR1 wherein, R is selected from hydrogen, loweralkyl, trifluoromethyl, carboxyl, or loweralkoxycarbonyl; R1 and R2 are hydrogen or loweralkyl; Z is trifluoromethyl or halogen; the optical isomers and pharmaceutically acceptable salts thereof; two of the preferred compounds of the invention are fenfluramine and norfenfluramine.

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