882029-86-9Relevant academic research and scientific papers
Regioselective functionalization of trisubstituted pyridines using a bromine-magnesium exchange
Ren, Hongjun,Knochel, Paul
, p. 726 - 728 (2008/02/03)
A tosyloxy substituent in position 2 allows a highly regioselective Br/Mg exchange reaction on 3,5-dibromopyridine derivatives using iso- PrMgCl·LiCl. The resulting functionalized pyridylmagnesium reagents react with various electrophiles in position 3. A
