88205-32-7

Basic information

• Product Name: 6,7-dimethoxy-1-(3',4'-dimethoxyphenyl)-2-nitroso-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 6,7-dimethoxy-1-(3',4'-dimethoxyphenyl)-2-nitroso-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 88205-32-7
• Molecular Weight: 372.421
• Mol File: 88205-32-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6,7-dimethoxy-1-(3',4'-dimethoxyphenyl)-2-nitroso-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-dimethoxy-1-(3',4'-dimethoxyphenyl)-2-nitroso-1,2,3,4-tetrahydroisoquinoline(88205-32-7)
• EPA Substance Registry System: 6,7-dimethoxy-1-(3',4'-dimethoxyphenyl)-2-nitroso-1,2,3,4-tetrahydroisoquinoline(88205-32-7)

Safety Data

• Hazardous Substances Data: 88205-32-7(Hazardous Substances Data)

Upstream product

• 88205-31-6 tetrahydropapaverine hydrobromide 
• 91790-53-3 1,2,3,4-tetrahydro-6,7-dimethoxy-2-(3,4-dimethoxybenzyl)isoquinoline 

Downstream Products

• 91790-53-3 1,2,3,4-tetrahydro-6,7-dimethoxy-2-(3,4-dimethoxybenzyl)isoquinoline 
• 16620-96-5 2-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Relevant articles and documents

Electrochemical Oxidation of Aromatic Ethers. Part 8. Evidence of Homogeneous Electron Transfer during the 'Low Potential' Oxidation of Laudanosine

Photolysis of N-amino- and N-nitroso-derivatives of 1,2,3,4-tetrahydropapaverine fails to produce aryl-aryl coupled products analogous to O-methylflavinantine.Instead both the 1- and 2-substituents of the heterocyclic ring are cleaved to give 6,7-dimethoxy-3,4-dihydroisoquinolines and veratraldehyde, the latter being an oxidation product of the 3,4-dimethoxybenzyl radical and/or cation.From this evidence, and the results of an electrolysis experiment carried out at high dilution, it is considered that the anodic cyclisation of laudanosine to O-methylflavinantine proceeds through homogeneous electron transfer rather than via homoconjugative activation within the intermediate radical cation as proposed by other workers.