88205-40-7

Upstream product

• 186581-53-3 diazomethane 
• 58-74-2 Papaverine 
• 108-24-7 acetic anhydride 
• 36016-40-7 mesitylenesulfonylhydroxylamine 
• 88205-38-3 N-aminopapaverinium mesitylenesulphate 

Downstream Products

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 88205-36-1 1-(3',4'-dimethoxybenzyl)-6,7-dimethoxy-2-(N-methylacetamido)-1,2,3,4-tetrahydroisoquinoline 
• 88205-41-8 2-acetamido-6,7-dimethoxy-1-(3',4'-dimethoxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinolinium iodide 
• 93-03-8 (3,4-dimethoxyphenyl)methanol 
• 88205-34-9 2-acetamido-1-(3',4'-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Electrochemical Oxidation of Aromatic Ethers. Part 8. Evidence of Homogeneous Electron Transfer during the 'Low Potential' Oxidation of Laudanosine

Photolysis of N-amino- and N-nitroso-derivatives of 1,2,3,4-tetrahydropapaverine fails to produce aryl-aryl coupled products analogous to O-methylflavinantine.Instead both the 1- and 2-substituents of the heterocyclic ring are cleaved to give 6,7-dimethoxy-3,4-dihydroisoquinolines and veratraldehyde, the latter being an oxidation product of the 3,4-dimethoxybenzyl radical and/or cation.From this evidence, and the results of an electrolysis experiment carried out at high dilution, it is considered that the anodic cyclisation of laudanosine to O-methylflavinantine proceeds through homogeneous electron transfer rather than via homoconjugative activation within the intermediate radical cation as proposed by other workers.