882053-90-9

Upstream product

• 13379-98-1 3-[N-(4-methylphenylsulfonyl)amino]propan-1-ol 
• 3355-28-0 1-Bromo-2-butyne 
• 286376-23-6 4-methyl-N-(prop-1-yn-1-yl)benzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 908000-27-1 N-{3-(tert-butyldimethylsilyloxy)propyl}-N-tosylbut-2-yn-1-amine 

Downstream Products

• 908000-28-2 methyl (E)-5-((N-(but-2-yn-1-yl)-4-methylphenyl)sulfonamid)pent-2-enoate 

Relevant academic research and scientific papers

Nickel-mediated cyclization of enynes under an atmosphere of carbon dioxide

Nickel-mediated carboxylation of α,ω-enyne was investigated. In the presence of a stoichiometric amount of zero-valent nickel complex, enynes having an electron-withdrawing group on alkene reacted with carbon dioxide via intramolecular cyclization to affo

Synthesis of 3,4-disubstituted piperidines by carbonyl ene and prins cyclizations: Switching between kinetic and thermodynamic control with Bronsted and Lewis acid catalysts

A novel approach to cis and trans 3,4-disubstituted piperidines is described. Carbonyl ene cyclization of aldehydes 4a-e catalyzed by MeAlCl 2 in refluxing chloroform afforded the trans piperidines 7a-e with diastereomeric ratios of up to 93:7,