88208-76-8Relevant academic research and scientific papers
Approaches to the Synthesis of 4-Hydroxypiloquinone
Giles, Robin G. F.,Mitchell, Peter R. K.,Sargent, Melvyn V.
, p. 2147 - 2152 (2007/10/02)
The synthesis of 4-acetoxy-1,8-dihydroxy-2-methyl-3-(4-methylpentanoyl)phenanthrene-9,10-quinone (30) and 1,4,8-trimethoxy-2-methyl-3-(4-methylpentanoyl)phenanthrene-9,10-quinone (33), derivatives of the mould metabolite 4-hydroxypiloquinone (2) are desribed.Photocyclization of methyl 2,2',5,6'-tetramethoxy-3-methylstilbene-4-carboxylate (21) provided methyl 1,4,8-trimethoxy-2-methylphenanthrene-3-carboxylate (22), suitable for further elaboration into the natural derivatives.
