882096-00-6

Basic information

• Product Name: 3-bromo-4-isopropoxybenzamide
• Synonyms: 3-bromo-4-isopropoxybenzamide
• CAS NO: 882096-00-6
• Molecular Formula: C10H12BrNO2
• Molecular Weight: 258.11178
• Mol File: 882096-00-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 323.8±27.0 °C(Predicted)
• Appearance: /
• Density: 1.420±0.06 g/cm3(Predicted)
• PKA: 15.94±0.50(Predicted)
• CAS DataBase Reference: 3-bromo-4-isopropoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-4-isopropoxybenzamide(882096-00-6)
• EPA Substance Registry System: 3-bromo-4-isopropoxybenzamide(882096-00-6)

Safety Data

• Hazardous Substances Data: 882096-00-6(Hazardous Substances Data)

Upstream product

• 83466-37-9 4-isopropoxy-1-ethylbenzene 

Relevant articles and documents

Direct Transformation of Ethylarenes into Primary Aromatic Amides with N -Bromosuccinimide and I2-Aqueous NH3

A variety of ethylarenes were converted into the corresponding primary aromatic amides in good yields via treatment with N-bromosuccinimide in the presence of a catalytic amount of 2,2′-azobis(isobutyronitrile) in a mixture of ethyl acetate and water, acetonitrile and water, or chloroform and water, followed by reaction with molecular iodine and aq NH3 in one pot. It was found that aryl α-bromomethyl ketones and/or aryl methyl ketones were formed at the first reaction step and their iodoform-type reaction occurred at the second reaction step to provide primary aromatic amides. The present reaction is a useful and practical transition-metal-free method for the preparation of primary aromatic amides from ethylarenes. (Chemical Equation Presented).