882185-11-7

Basic information

• Product Name: (5S)-3-{4-[4-(2,1,3-benzoxadiazol-5-yl)piperazin-1-yl]-3-fluorophenyl}-5-[(isoxazol-3-ylamino)methyl]-1,3-oxazolidm-2-one
• Synonyms: (5S)-3-{4-[4-(2,1,3-benzoxadiazol-5-yl)piperazin-1-yl]-3-fluorophenyl}-5-[(isoxazol-3-ylamino)methyl]-1,3-oxazolidm-2-one
• CAS NO: 882185-11-7
• Molecular Weight: 461.493
• Mol File: 882185-11-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5S)-3-{4-[4-(2,1,3-benzoxadiazol-5-yl)piperazin-1-yl]-3-fluorophenyl}-5-[(isoxazol-3-ylamino)methyl]-1,3-oxazolidm-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5S)-3-{4-[4-(2,1,3-benzoxadiazol-5-yl)piperazin-1-yl]-3-fluorophenyl}-5-[(isoxazol-3-ylamino)methyl]-1,3-oxazolidm-2-one(882185-11-7)
• EPA Substance Registry System: (5S)-3-{4-[4-(2,1,3-benzoxadiazol-5-yl)piperazin-1-yl]-3-fluorophenyl}-5-[(isoxazol-3-ylamino)methyl]-1,3-oxazolidm-2-one(882185-11-7)

Safety Data

• Hazardous Substances Data: 882185-11-7(Hazardous Substances Data)

Upstream product

• 154590-63-3 [N-3-(1-tert-butoxycarbonyl)-4-(2-fluoro-4-piperazinyl)-2-oxo-5-oxazolidinyl]methyl methanesulfonate 
• 264600-97-7 3-N-(t-butoxycarbonyl)amino-1,2-isoxazole 

Downstream Products

• 882185-14-0 (5S)-3-(3-fluoro-4-piperazin-1-ylphenyl)-5-[(isoxazol-3-ylamino)methyl]-1,3-oxazolidin-2-one 

Relevant articles and documents

OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS

The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.